G蛋白偶联受体30抗体_价格_上海联迈生物工程有限公司

产品详情

G蛋白偶联受体30抗体

英文名称 GPR30

中文名称 G蛋白偶联受体30抗体

别名 G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymphocyte-derived G-protein coupled receptor; LYGPR; GPCR-BR; CEPR; CMKRL2; DRY12; GPER.

研究领域细胞生物神经生物学信号转导细胞膜受体 G蛋白偶联受体 G蛋白信号

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog,

产品应用 WB=1:500-2000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 42kDa

细胞定位细胞核细胞浆细胞膜细胞外基质

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human GPR30:251-350/375 <Extracellular>

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 G protein-coupled receptors (GPRs, or GPCRs) contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GRP30 is a member of this family and is an orphan receptor. GPR30 expression has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, and spleen. In brain, GPR30 is expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen. However, unlike other known G protein-coupled receptors, GPR30 localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives.
GPR30是一种膜性雌激素蛋白受体又称非基因型雌激素膜性受体GPR30。GPR30受体广泛表达于海马、下丘脑、子宫、卵巢、乳腺、骨和心血管等全身多个系统、器官和组织,在细胞内主要定位于细胞膜、内质网、线粒体和高尔基体。 GPER与雌激素结合, ERK、PI3K/AKT)、 cAMP等第二信使途径发挥快速非基因效应,在神经系统、生殖系统、运动系统和心血管系统中发挥重要的生理作用。

G蛋白偶联受体30抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于G蛋白偶联受体30抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应G蛋白偶联受体30抗体外，上海联迈生物工程有限公司还可为您提供酪氨酸羟化酶抗体、胰岛素样生长因子1抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM20643R
CAS号：