凋亡抑制蛋白抗体_价格_上海联迈生物工程有限公司

产品详情

凋亡抑制蛋白抗体

英文名称 Livin

中文名称凋亡抑制蛋白抗体

别名 Baculoviral IAP repeat containing 7; Baculoviral IAP repeat containing protein 7; BIRC 7; BIRC7; BIRC7_HUMAN; KIAP; Kidney inhibitor of apoptosis protein; LIVIN; Livin inhibitor of apotosis; Melanoma inhibitor of apoptosis protein; ML IAP; MLIAP; RING finger protein 50; RNF 50; RNF50; Inhibitors of apoptosis proterins Livin.

研究领域肿瘤细胞生物信号转导细胞凋亡细胞周期蛋白

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Cow, Rabbit, Sheep,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 33kDa

细胞定位细胞核细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human Livin:41-100/298

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.

Livin—属于凋亡蛋白抑制因子家族（inhibitor of apoptosis proteins，IAP）
Livin是凋亡抑制蛋白家族的新成员，主要通过抑制Caspases蛋白发挥抑制细胞凋亡的作用,主要在胎盘组织中表达，同时在一些肿瘤组织中呈高表达，尤其是在黑色素瘤细胞系表达水平最高。
经研究表明，Livin与肿瘤的发生、发展关系密切,是一个有潜在价值的肿瘤标志物，此外，反义Livin以及Livin活性抑制物的研究有望成为肿瘤治疗的新靶点。

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM20731R
CAS号：