肿瘤坏死因子配体超家族成员10C

肿瘤坏死因子配体超家族成员10C

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM2083R
CAS号:
上海联迈生物工程有限公司
银牌会员6年生产商
关注展位 全部试剂
产品详情

1.png

肿瘤坏死因子配体超家族成员10C

 

英文名称    DcR1    

中文名称    肿瘤坏死因子配体超家族成员10C    

别    名    Decoy receptor 1;TNFRSF10C; CD263; DcR 1; LIT; Lymphocyte inhibitor of TRAIL; TNF Related Apoptosis Inducing Ligand Receptor 3; TNFRSF10C; TRAIL R3; TRAIL receptor 3; TRAIL Receptor Without An Intracellular Domain; TRAILR3; TRID; Tumor Necrosis Factor Receptor Superfamily Member 10C; DcR1; TRAIL-R3.      

研究领域    肿瘤  细胞生物  免疫学  信号转导  细胞凋亡  转录调节因子  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    23kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TNFRSF10C:51-150/259     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008].
DcR1因缺乏细胞内信号传导系统而不能传递凋亡信号,但能竞争性与TRAIL(肿瘤坏死因子相关凋亡诱导配体)结合,有干扰凋亡信号的传导作用。   


肿瘤坏死因子配体超家族成员10C信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于肿瘤坏死因子配体超家族成员10C报价、型号、参数等信息, 欢迎来电或留言咨询。除供应肿瘤坏死因子配体超家族成员10C外,上海联迈生物工程有限公司还可为您提供肿瘤抑制基因P53蛋白/野生型P53抗体、Bcl-2抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

相关试剂 更多

相关产品

当前位置: 仪器信息网 LMAI-BIO 试剂 肿瘤坏死因子配体超家族成员10C

关注

拨打电话

留言咨询