供货周期: | 现货 |
品牌: | LMAI Bio |
型号: | 50ul/100ul/200ul |
货号: | LM2570R |
CD26抗体
英文名称 CD26
中文名称 CD26抗体
别 名 ADCP2; DPPIV; Dipeptidyl peptidase 4; ADABP; ADCP 2; Adenosine deaminase complexing protein 2; CD 26; CD26; CD26 antigen 3; Dipeptidyl peptidase 4; Dipeptidyl peptidase iv; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV; DPP 4; DPP IV; DPP4; Intestinal dipeptidyl peptidase; T cell activation antigen CD26; TP 103; TP103.
Specific References (2) | bs-2570R has been referenced in 2 publications.
[IF=0.68] Lu Z, Qi L, Bo XJ, Liu GD, Wang JM, Li G. Expression of CD26 and CXCR4 in prostate carcinoma and its relationship with clinical parameters. CD26 and CXCR4 expression shows correlation with prostate cancer. J Res Med Sci 2013;18:647-52 Human.
PubMed:24379839
[IF=5.99] Eckerle, Isabella. "Replicative Capacity of MERS Coronavirus in Livestock Cell Lines." Emerging Infectious Diseases 2014 Goat.
PubMed:24457147
研究领域 肿瘤 细胞生物 免疫学 干细胞 细胞凋亡 细胞膜受体 细胞粘附分子 细胞表面分子 糖蛋白 淋巴细胞 t-淋巴细胞 b-淋巴细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 Flow-Cyt=3μg/Test (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
细胞定位 细胞浆 细胞膜 细胞外基质 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD26:661-766/766
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3.
CD26是细胞表面上一种氨基肽酶,具有丝氨酸蛋白酶活性,属于丝氨酸蛋白酶s9b家族,分布于多种细胞表面或游离于胞浆中,具有高度保守的蛋白水解酶活性. 还是一种细胞膜受体、共刺激分子,参与机体免疫调节、细胞迁移、细胞黏附和细胞凋亡.
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