白介素3受体a链抗体

白介素3受体a链抗体

英文名称    IL3R alpha    

中文名称    白介素3受体a链抗体    

别    名    IL-3R alpha; IL3R alpha; Interleukin-3 receptor subunit alpha precursor; CD 123; CD123; CD123 antigen; hIL3Ra; IL 3 receptor subunit alpha; IL 3R alpha; IL 3R; IL 3R subunit alpha; IL3 receptor subunit alpha; IL3R alpha; IL3R; IL3RAY; IL3RX; IL3RY; Interleukin 3 receptor alpha; Interleukin 3 receptor, alpha (low affinity); Interleukin-3 receptor; MGC34174; IL3RA_HUMAN.       

研究领域    细胞生物  免疫学  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse,     

产品应用    ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /test IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    40kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human IL-3R alpha:201-300/378 <Extracellular>    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]   白细胞介素3受体α(IL-3Rα)又称CD123，是造血生长因子受体家族成员,CD123是未分化白血病干细胞的特异标志.在细胞信号转导、细胞凋亡及血液肿瘤发生中起重要作用.