磷酸化糖原合酶激酶3α抗体_价格_上海联迈生物工程有限公司

产品详情

磷酸化糖原合酶激酶3α抗体

英文名称 Phospho-GSK3 alpha (Ser21)

中文名称磷酸化糖原合酶激酶3α抗体

别名 GSK3 alpha (phospho S21); p-GSK3 alpha (phospho S21); GSK3a(Phospho-Ser21); P-GSK3 alpha(Ser21); Gsk3a; GSK 3 alpha; GSK-3 alpha; GSK3 alpha; Glycogen synthase kinase-3 alpha; GSK 3 alpha; DKFZp686D0638; GSK 3A; GSK3A; GSK3alpha; GSK3A_HUMAN; Glycogen synthase kinase 3 alpha; Serine/threonine-protein kinase GSK3A.

产品类型磷酸化抗体

研究领域肿瘤信号转导激酶和磷酸酶

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 53kDa

细胞定位细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthesised phosphopeptide derived from human GSK3 alpha around the phosphorylation site of Ser21:RT(p-S)SF

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3161R
CAS号：