磷酸化原癌基因c-Jun抗体_价格_上海联迈生物工程有限公司

产品详情

磷酸化原癌基因c-Jun抗体

英文名称 phospho-c-Jun (Ser73)

中文名称磷酸化原癌基因c-Jun抗体

别名 c-Jun (phospho Ser73); c-Jun (phospho S73); c-Jun (phospho S73); p-c-Jun (phospho S73) ; Transcription factor AP-1; Jun oncogene; JUN; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.

产品类型磷酸化抗体

研究领域肿瘤细胞生物信号转导细胞凋亡转录调节因子表观遗传学

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 WB= ELISA= IHC-P= IHC-F= Flow-Cyt=1μg /Test IF= （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 43kDa

细胞定位细胞核

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated Synthesised phosphopeptide derived from human c-Jun around the phosphorylation site of Ser73:LA(p-S)PE

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3172R
CAS号：