磷酸化微管相关蛋白2抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM3259R
CAS号:
上海联迈生物工程有限公司
银牌会员6年生产商
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磷酸化微管相关蛋白2抗体

 

英文名称    Phospho-MAP2 (Ser136)    

中文名称    磷酸化微管相关蛋白2抗体    

别    名    MAP2(Phospho Ser136); MAP2 (phospho S136); p-MAP2 (phospho S136); MAP2(Phospho S136); MAP2(Phospho-Ser136); p-MAP2(Phospho-Ser136); DKFZp686I2148; Dendrite specific MAP; DKFZp686I2148; MAP 2; MAP-2; MAP2; MAP2_HUMAN; MAP2A; MAP2B; MAP2C; Microtubule associated protein 2; Microtubule-associated protein 2; Mtap 2.      

产品类型    磷酸化抗体     

研究领域    免疫学  神经生物学  信号转导  干细胞  细胞凋亡  细胞类型标志物  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,     

产品应用    ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=0.2μg /Test IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    70/201kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human MAP2 around the phosphorylation site of Ser136:PP(p-S)P     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.    

微管相关蛋白 2(MAP-2)是一种磷蛋白质,在正常脑组织中,主要存在于神经元的胞体、树突和树突棘,是脑内最丰富的蛋白之一。MAP-2在其调节微管的聚合作用和微管的稳定性以及对神经元轴突和树突的发生、延长、稳定和突触可塑性调节具有重要作用。

磷酸化微管相关蛋白2抗体信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于磷酸化微管相关蛋白2抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应磷酸化微管相关蛋白2抗体外,上海联迈生物工程有限公司还可为您提供KCTD6蛋白抗体、钾离子通道多聚体结构域蛋白19抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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