磷酸化马铃薯球蛋白(结节性硬化)抗体_价格

产品详情

磷酸化马铃薯球蛋白(结节性硬化)抗体

英文名称 Phospho-Tuberin (Tyr1571)

中文名称磷酸化马铃薯球蛋白(结节性硬化)抗体

别名 Tuberin(phospho Y1571); Tuberin (phospho Tyr1571); p-Tuberin (Tyr1571); FLJ43106; LAM; OTTHUMP00000158940; OTTHUMP00000198394; OTTHUMP00000198395; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2; Tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog.

产品类型磷酸化抗体

研究领域肿瘤免疫学信号转导

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 180-220kDa

细胞定位细胞浆细胞膜

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated Synthesised phosphopeptide derived from human Tuberin around the phosphorylation site of Thr1571:R(p-Y)TE

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.

Tuberin 为180kD-220的蛋白产生于结节性硬化（TSC-2）位于染色体16的基因。结节性硬化为常染色体疾病已知为斑痣性错构瘤病其特征为广泛性发展呈良性生长，在许多组织与器官中描述为错构瘤。Tuberin被认为在GTPase活动性蛋白中起作用调节细胞内吞与作为肿瘤抑制子。Tuberin低水平广泛性表达在大多数组织中，而在皮层神经元、小脑浦肯野氏细胞、脊索运动神经元、胰岛B细胞、心肌、肾脏与皮肤的小血管中表达增加。

磷酸化马铃薯球蛋白(结节性硬化)抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于磷酸化马铃薯球蛋白(结节性硬化)抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应磷酸化马铃薯球蛋白(结节性硬化)抗体外，上海联迈生物工程有限公司还可为您提供B细胞迁移基因2抗体、蛋白质磷酸酶-2A抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3443R
CAS号：