细胞分化周期CDC42蛋白抗体_价格_上海联迈生物工程有限公司

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细胞分化周期CDC42蛋白抗体

英文名称 CDC42

中文名称细胞分化周期CDC42蛋白抗体

别名 CDC 42; CDC42Hs; Cell division control protein 42 homolog; Cell division cycle 42; Cell division cycle 42 isoform 1; Cell division cycle 42 isoform 2; dJ224A6.1.1; dJ224A6.1.2; G25K; G25K GTP binding protein; Growth regulating protein; GTP binding protein 25kD; Small GTP binding protein CDC42; CDC42_HUMAN.

研究领域肿瘤免疫学细胞周期蛋白转录调节因子

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 25kDa

细胞定位细胞浆细胞膜

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human CDC42:101-191/191

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].

Cdc42，是细胞骨架和细胞极化的重要调节蛋白，在减数分裂和卵母细胞成熟过程中有重要的作用，尤其在细胞分化，迁移过程中起到一定的作用,目前在肿瘤研究中得到了重视。

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3555R
CAS号：