磷酸化斑联蛋白抗体_价格_上海联迈生物工程有限公司

产品详情

磷酸化斑联蛋白抗体

英文名称 Phospho-Zyxin (Ser142+Ser143)

中文名称磷酸化斑联蛋白抗体

别名 Zyxin (phospho S142); p-Zyxin (phospho S142); ESP 2; ESP2; HED 2; HED2; ZYX; ZYX protein; Zyxin 2; Zyxin2; ZYX_HUMAN.

产品类型磷酸化抗体

研究领域免疫学染色质和核信号信号转导细胞凋亡转录调节因子

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep,

产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 61kDa

细胞定位细胞核细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated Synthesised phosphopeptide derived from human Zyxin around the phosphorylation site of Ser142/Ser143:101-200/572

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].

斑联蛋白(Zyxin)与细胞附着及信号转导相关,是肌动蛋白丝装配的调节物，在结构和功能上将细胞外配体与细胞骨架连接。

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3620R
CAS号：