草酰琥珀酸脱羧酶抗体_价格_上海联迈生物工程有限公司

产品详情

草酰琥珀酸脱羧酶抗体

英文名称 IDH2

中文名称草酰琥珀酸脱羧酶抗体

别名 mitochondrial; ICD-M; IDH; IDH2; IDHP_HUMAN; IDP; Isocitrate dehydrogenase [NADP]; Isocitrate dehydrogenase [NADP], mitochondrial; mNADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase.

研究领域肿瘤细胞生物免疫学染色质和核信号转录调节因子激酶和磷酸酶新陈代谢

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog, Horse,

产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=0.2ug/test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 51kDa

细胞定位细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human IDH2:251-350/452

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.

IDH2又称异柠檬酸脱氢酶，他有有两种类型的酶：以NAD为辅酶的酶（EC1．1．1．41）和NADP的酶（EC1．1．1．42），两者催化同一反应。在胞浆中以NADP为辅酶，在线粒体内膜以NAD为辅酶。　　 IDH2在三羧酸循环中正常起作用的是NAD为辅酶的酶，他是提供为ADP激活的变构酶。

草酰琥珀酸脱羧酶抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于草酰琥珀酸脱羧酶抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应草酰琥珀酸脱羧酶抗体外，上海联迈生物工程有限公司还可为您提供FLJ37201蛋白抗体、锌指蛋白778抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM3947R
CAS号：