促代谢型谷氨酸受体2抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM4769R
CAS号:
上海联迈生物工程有限公司
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促代谢型谷氨酸受体2抗体

 

英文名称    Metabotropic Glutamate Receptor 2    

中文名称    促代谢型谷氨酸受体2抗体    

别    名    Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GLUR2; GLURB; Glutamate receptor metabotropic 2; Metabotropic Glutamate Receptor 2; GPRC1B; GRM 2; Grm2; mGlu 2; MGlu2; MGLUR 2; Mglur2; GRM2_HUMAN.      

研究领域    肿瘤  细胞生物  免疫学  信号转导  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    96kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human GRM2/GLUR2:151-250/879 <Extracellular>    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
谷氨酸受体-代谢能2;主要参与细胞信号转导及突触传递,在G蛋白偶联受体蛋白信号转导途径中有一定的作用,并且有负调控腺苷酸环化酶的作用,为膜性蛋白,在胞膜、胞浆中表达。   


促代谢型谷氨酸受体2抗体信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于促代谢型谷氨酸受体2抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应促代谢型谷氨酸受体2抗体外,上海联迈生物工程有限公司还可为您提供粘蛋白-1抗体、CD19抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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