| 供货周期： | 现货 |
| 品牌： | LMAI Bio |
| 规格： | 50ul/100ul/200ul |
| 货号： | LM5449R |
| CAS号： |
磷酸化胰岛素样生长因子1受体抗体
英文名称 phospho-IGF1R (Tyr1165 + Tyr1166)
中文名称 磷酸化胰岛素样生长因子1受体抗体
别 名 IGF1 Receptor (phospho Y1165 + Y1166); p-IGF1 Receptor (phospho Y1165 + Y1166); IGF-1R (Phospho-Tyr1165/Tyr1166); IGF1R (phospho Y1165+Y1166); IGF1R (phospho Tyr1165+Tyr1166); p-IGF1R (Tyr1165+Tyr1166); phospho-IGF1R (Tyr1166+Tyr1167)rat; phospho-IGF1R (Tyr1166+Tyr1167)mo; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1 Receptor; IGF1R_HUMAN; IGF-IR.
产品类型 磷酸化抗体
研究领域 信号转导 生长因子和激素 转录调节因子 激酶和磷酸酶 细胞膜受体 糖尿病
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
产品应用 ELISA=1:500-1000 Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 150kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166:TD(p-Y)(p-Y)RK
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].
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