磷酸化髓鞘碱性蛋白抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM5474R
CAS号:
上海联迈生物工程有限公司
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磷酸化髓鞘碱性蛋白抗体

 

英文名称    phospho-MBP (Thr232)    

中文名称    磷酸化髓鞘碱性蛋白抗体    

别    名    MBP(phospho T232); Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP.      

产品类型    磷酸化抗体     

研究领域    免疫学  神经生物学  信号转导  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    33kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human MBP around the phosphorylation site of Thr232:PR(p-T)PP     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    Oligodendrocyte Marker
The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.    

少突胶质细胞标志物。
主要用于脊髓脱髓鞘病-脊髓多发硬化症的研究。 MBP髓鞘碱性蛋白和髓鞘相伴糖蛋白是多发性硬化的自身免疫攻击的靶。


磷酸化髓鞘碱性蛋白抗体信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于磷酸化髓鞘碱性蛋白抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应磷酸化髓鞘碱性蛋白抗体外,上海联迈生物工程有限公司还可为您提供线粒体转录终止因子2抗体、MSTO1蛋白抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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