磷酸化非受体型蛋白酪氨酸磷酸酶7抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM5557R
CAS号:
上海联迈生物工程有限公司
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磷酸化非受体型蛋白酪氨酸磷酸酶7抗体

 

英文名称    phospho-PTPN7 (Ser246)    

中文名称    磷酸化非受体型蛋白酪氨酸磷酸酶7抗体    

别    名    PTPN7(phospho S246); BPTP 4; BPTP4; Dual specificity phosphatase 1; Hematopoietic protein tyrosine phosphatase; LC PTP; LCPTP; LPTP; Protein tyrosine phoshatase non receptor type stress induced; Protein tyrosine phoshatase nonreceptor type stress induced; Protein tyrosine phosphatase LC PTP; Protein tyrosine phosphatase non receptor type 7; PTPN 7; PTPNI; Tyrosine protein phosphatase non receptor type 7; PTN7_HUMAN.      

产品类型    磷酸化抗体     

研究领域    肿瘤  免疫学  信号转导  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Mouse, Rat,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    40kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human PTPN7 around the phosphorylation site of Ser246:CR(p-S)VK     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
   



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