丝裂原活化蛋白激酶8相互作用蛋白1抗体_价格

产品详情

丝裂原活化蛋白激酶8相互作用蛋白1抗体

英文名称 JIP1/MAPK8IP1

中文名称丝裂原活化蛋白激酶8相互作用蛋白1抗体

别名 C jun amino terminal kinase interacting protein 1; IB 1; IB1; Islet brain 1; JIP 1; JNK interacting protein 1; JNK MAP kinase scaffold protein 1; MAPK8IP 1; MAPK8IP1; Mitogen activated protein kinase 8 interacting protein 1; PRKM8 interacting protein; PRKM8IP; JIP1_HUMAN.

研究领域肿瘤信号转导激酶和磷酸酶细胞骨架

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 77kDa

细胞定位细胞核细胞浆细胞膜细胞外基质

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human JIP1/MAPK8IP1:425-524/711

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

丝裂原活化蛋白激酶8相互作用蛋白1抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于丝裂原活化蛋白激酶8相互作用蛋白1抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应丝裂原活化蛋白激酶8相互作用蛋白1抗体外，上海联迈生物工程有限公司还可为您提供巢蛋白/神经上皮干细胞蛋白抗体、GFAP胶质纤维酸性蛋白抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM6255R
CAS号：