| 供货周期： | 现货 |
| 品牌： | LMAI Bio |
| 规格： | 50ul/100ul/200ul |
| 货号： | LM8545R |
| CAS号： |
肿瘤坏死因子受体相关蛋白4抗体
英文名称 TRAF4
中文名称 肿瘤坏死因子受体相关蛋白4抗体
别 名 CART 1; CART1; TRAF 4; TRAF-4; TRAF4_HUMAN; cysteine rich domain associated with ring and TRAF domain; Cysteine rich domain associated with RING and Traf domains protein 1; Malignant 62; metastatic lymph node gene 62 protein; MLN 62; MLN62; RING finger protein 83; RNF 83; RNF83; TNF receptor associated factor 4; TRAF 4; tumor necrosis receptor-associated factor 4A.
研究领域 肿瘤 细胞生物 免疫学 染色质和核信号 信号转导 生长因子和激素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit, Sheep,
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAF4:1-100/470
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].
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