磷酸化蛋白激酶C/p-PKC ε抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM8608R
CAS号:
上海联迈生物工程有限公司
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磷酸化蛋白激酶C/p-PKC ε抗体

 

英文名称    phospho-PKC Epsilon (Ser729)    

中文名称    磷酸化蛋白激酶C/p-PKC ε抗体    

别    名    PKC epsilon (phospho S729); PKC Epsilon (phospho Ser729); p-PKC Epsilon (Ser729); PKC-A; PKC alpha; AAG6; Aging associated gene 6; PICK 1; PKC A; PKCA; PKC A; PRKCA; Protein Kinase C alpha; Protein kinase C alpha type; KPCE_HUMAN.      

产品类型    磷酸化抗体     

研究领域    肿瘤  免疫学  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    84kDa    

细胞定位    细胞核 细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human PKCE around the phosphorylation site of Ser729:FS(p-Y)FG     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008].    


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