热休克蛋白-70单克隆抗体

参考价:¥1580
供货周期: 现货
品牌: LMAI Bio
规格: 50ul/100ul/200ul
货号: LM33048M
CAS号:
上海联迈生物工程有限公司
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热休克蛋白-70单克隆抗体

 

英文名称    HSP70    

中文名称    热休克蛋白-70单克隆抗体    

别    名    HSP70; HSP-70; HSP 70; Heat shock 70 kDa protein 1; heat shock 70kDa protein 1A; Heat shock 70kDa protein 1B; Heat shock induced protein; heat shock protein 70; HSP70 1; HSP70 2; HSP70.1; HSP72; HSPA1; HSPA1A; HSPA1B; XXbac BCX40G17.3 001; Heat shock 70 kDa protein 1A/1B; HSP71A_HUMAN; Hspa1a; Hsp70-1; HSP72; Hspa1; Hspa1b; Heat shock 70 kDa protein 1A/1B; shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2.      

研究领域    肿瘤  信号转导  转录调节因子      

抗体来源    Mouse    

克隆类型    Monoclonal    

克 隆 号    5G10    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    70kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human HSP70:     

亚    型    IgG    

纯化方法    affinity purified by Protein G    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008].    

信号传导(Signaling Intermediates)
HSP-70是细胞受应激原刺激后诱导产生的一组应激蛋白,与肿瘤发生、增殖及分化有关。
环境和病生理性应激原均可导致肌体合成一组应急蛋白既热休克蛋白。许多热休克蛋白,包括HSP70家族成员,均参与蛋白的变性-复性、折叠-解折叠、运输-易位、活化-非活化和分泌等过程。
HSP70与类固醇受体、肌动蛋白、P53等蛋白密切相关。HSP70还参与热应激原、细胞毒药物和其他损伤所引起的应急反应,对机体起一定的保护作用。

热休克蛋白-70单克隆抗体信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于热休克蛋白-70单克隆抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应热休克蛋白-70单克隆抗体外,上海联迈生物工程有限公司还可为您提供囊泡对接蛋白p115抗体、泛素激活酶2B抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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