环腺苷酸应答元件结合蛋白单克隆抗体_价格

产品详情

环腺苷酸应答元件结合蛋白单克隆抗体

英文名称 CREB-1

中文名称环腺苷酸应答元件结合蛋白单克隆抗体

别名 Active transcription factor CREB; cAMP response element binding protein; cAMP responsive element binding protein 1; CREB 1; CREB1; MGC9284; Transactivator protein;CREB.

研究领域信号转导

抗体来源 Mouse

克隆类型 Monoclonal

克隆号 6B4

交叉反应 Human, Mouse,

产品应用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 37kDa

细胞定位细胞核

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human CREB-1:

亚型 IgG

纯化方法 affinity purified by Protein G

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory. CREB knock out mice show diminished learning ability.

环腺苷酸应答元件结合蛋白(cAMP responsive element binding protein, CREB)是真核细胞转录因子，属于ATF/CREB家族。参与由cAMP或某些病毒蛋白质所诱导基因转录的调节。

环腺苷酸应答元件结合蛋白单克隆抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于环腺苷酸应答元件结合蛋白单克隆抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应环腺苷酸应答元件结合蛋白单克隆抗体外，上海联迈生物工程有限公司还可为您提供同源盒蛋白A1抗体、T细胞白血病淋巴瘤蛋白3抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM33196M
CAS号：