Memberships:National Academy of Science；American Chemical Society - Agriculture Chemicals Division；AOAC International；Entomological Society of America；Society ofToxicology；International Society for the Study of Xenobiotics；ASPET - American Society for Pharmacology and Experimental Therapeutics Research Projects in Progress：Immunochemistry (260 articles) Develop the technologies for application of immunochemistry to toxicological & environmental research. Develop mono- and polyclonal based immunoassays for environmental contaminants. Develop immunoassay systems to evaluate human exposure. Explore monoclonal, polyclonal and cloned antibodies for biosensor development. Insect Research (240 articles) Exploit a fundamental understanding of insect developmental biology for the control of insect pests. Develop site-directed inhibitors for enzymes involved in juvenile hormone metabolism. Design chemical and biochemical agents for the disruption of insect development. Use cloned proteins expressed in baculovirus vectors for insect control. Investigate regulation of endocrine events at the molecular level. Mammalian Research (573 articles) Examine effect of hepatic enzymes on foreign compounds in diet & the influence of these compounds on hepaticenzymes. Examine the mechanism of action of nongenotoxic carcinogens & their influence on esterases, epoxide hydrolases,& glutathione transferases. Design selective inhibitors, substrates & purification systems for hepatic esterases & epoxide hydrolases.