高速梯度仪

液相色谱四元梯度比例阀 液相色谱四元梯度比例阀 生产商: 美国Parker系列18型液相色谱四元梯度比例阀( 4阀组件,已经3阀或2阀组件),为紧凑型安装, 应用于多种液体或气体的混合气路控制系统。它的所有与介质接触的部分都是Teflon（特氟龙）材质，可以直接连接Teflon接头和管线，减少了死体积。开闭的高速和高重复性使其理想的应用于小比例和低流量的液体和气体。 特点： －低功耗 －低死体积 －高循环寿命 －高速 －无需压力即可操作 规格参数 －供电电压：9VDC－ 阀体：特氟龙阀 －介质兼容性：腐蚀性液体和气体 －操作温度：4~66度 －接口：1/4-28螺纹 －推荐过滤：10微米 －操作压力：真空～20PSIG －通径：0.062"(1.6mm) －响应时间：小于12ms －泄露速率：气泡检测 －电压：12VDC 或24VDC

梯度PCR仪配件是真正意义上的梯度PCR热循环仪，适合聚合酶链式反应为特征的、以检测DNA/RNA为目的的各种病原体检测及基因分析。 梯度PCR仪配件特点 方便而灵活的模块更换设计 超大尺寸LCD显示屏 具有指导性的界面方便用户使用操作 超低噪音，节能，寿命长 外观漂亮大方 独特的旋转失速热调节功能 热盖可在任何角度停止 梯度PCR仪配件参数 容积：96x0.2mL, 54x0.5mL 温度范围：0-99℃ 最大加热速率：=4℃/s 均匀性：=0.3℃（95℃),=0.2℃（20-75℃） 最大制冷速率：=3.5℃/s 温度精度：=+/-0.2℃ 温度梯度范围：30-99℃ 梯度扩散：2-30℃ 梯度均匀性：=0.2℃ 加热盖温度：30-115℃ 可存储命令数：200 最大循环数：99 显示：5.7' ' LCD 尺寸：380x270x250 重量：7.2kg 孚光精仪是全球领先的进口精密科学仪器领导品牌服务商，拥有包括[PCR仪在内的齐全精密科学仪器品类，具有全球领先的制造工艺和质量控制体系。 我们国外工厂拥有超过3000种仪器的大型现代化仓库，可在下单后12小时内从国外直接空运发货，我们位于天津保税区的进口公司众邦企业（天津)国际贸易公司为客户提供全球零延误的进口通关服务。 更多关于梯度PCR仪价格等诸多信息，孚光精仪会在第一时间更新并呈现出来，了解更多内容请关注孚光精仪官方网站方便获取！

梯度PCR热循环仪配件是真正意义上的梯度PCR仪，适合聚合酶链式反应为特征的、以检测DNA/RNA为目的的各种病原体检测及基因分析。梯度PCR热循环仪配件特点方便而灵活的模块更换设计密封样品设计，用于低温保存,清洁和干燥双阶热盖压力调节器，确保完美密封镀金或镀银模块，增加热传导效率，实验更为有效超大尺寸高对比度LCD显示屏具有指导性的界面方便用户使用操作可调旋钮配置，适合各种试管断电内存保存功能超低噪音，节能，寿命长热盖可在任何角度停止金属材料盖子，更加安全可靠可以连接硬盘和鼠标可与计算机连接进行多功能控制Windows系统方便免费程序升级梯度PCR热循环仪配件参数容积：96x0.2mL, 54x0.5mL，96x0.2ml,77x0.5ml,384well温度范围：0-99℃最大加热速率：=4.5℃/s均匀性：=10.2℃（10秒后）最大制冷速率：=4℃/s温度精度：=+/-0.2℃温度梯度范围：30-99℃梯度扩散：1-30℃梯度均匀性：=0.2℃加热盖温度：20-110℃可存储命令数：1000最大循环数：999显示：5.7' ' LCD尺寸：380x270x250mm重量：7.8kg孚光精仪是全球领先的进口精密科学仪器领导品牌服务商，拥有包括[PCR仪在内的齐全精密科学仪器品类，具有全球领先的制造工艺和质量控制体系。我们国外工厂拥有超过3000种仪器的大型现代化仓库，可在下单后12小时内从国外直接空运发货，我们位于天津保税区的进口公司众邦企业（天津)国际贸易公司为客户提供全球零延误的进口通关服务。更多关于梯度PCR热循环仪价格等诸多信息，孚光精仪会在第一时间更新并呈现出来，想了解更多内容，请关注孚光精仪官方网站哦！

该系统专为二元高压梯度设计，功能与两台独立的泵部件相同，只是在硬件上做了相应的优化，使系统更小，便于客户的升级。另外该系统可将进样阀集成其中，使客户对二元高压梯度的扩展更为便利。

PCR基因扩增仪产品特点01-7003梯度PCR扩增仪具有升降温快速，控温精准度高，彩色触屏控制等特点，广泛应用于分子生物学，临床诊断，刑事侦查，疾病研究等。其梯度模块，拥有42℃的最宽梯度功能，可实现不同退火温度的精确控制，仅一次实验就能确定特定体系相应的最优退火温度。从而可在短时间内对PCR实验进行优化，提高PCR科研效率。● 高精度温度控制，整个体系温度均一性好● 快速的升降温速度，最大程度降低PCR的非特异性扩增的发生率● 彩色触屏，参数设定灵活，完美用户体验● 超宽42℃的梯度模块可设定不同的退火温度，一次实验即可优化PCR实验，提高科研效率● 可调热盖高度，模块兼容性强，适合多种PCR反应管● 超静音体系，外形小巧，性价比高订购信息产品型号样品数温度范围热盖温度显示精度最大变温速率断电保护01-70030.2mL PCR×96，8 联管×12 或96 孔PCR 板4-99℃50-110℃0.1℃ 3℃/s是更多产品信息，敬请关注上海希言科学仪器有限公司。

梯度降温盒 查看产品 Nalgene Mr. Frosty 冷冻容器 Thermo Scientific Nalgene Mr. Frosty 冷冻容器提供可重复的 -1℃/分钟的冷却速率，能够成功进行低温冻存和恢复。适用于多种低温管和样品瓶，可提供低成本的细胞低温冻存和恢复。System 100TM冻存管可保存大量样本。拥有最高级别的无菌认证（SAL 10-6）。适用于从普通冷藏温度（﹢4℃）到液氮气相的保存。CE认证，可存放医疗诊断样本。 冻存 1℃ 冷冻容器，&ldquo 梯度降温冻存盒&rdquo ，聚碳酸酯；蓝色高密度聚乙烯盖；白色高密度聚乙烯管槽；泡沫衬垫为成功冷冻保存细胞提供精确和良好重复性的冷却率：-1℃/分钟。仅需要100%的异丙醇和机械冷冻装置。标签上带有图示步骤说明。最多可容纳18个管瓶。支架可防止管瓶与醇接触-以防由于芯吸作用而造成污染、弄掉表情或在管槽上留下痕迹。装有醇的容器可在室温下存储，从而节约了冷冻空间。 目录编号 5100 -0001 盖尺寸 mm 120 高度× 直径 mm 86× 117 高度× 直径 in 3-7/16× 4-5/8 适用 NALGENE 冻存器具 1.0、1.2、1.5 和 2.0 ml 管瓶 每箱数量 1

产品描述:　　特点：与传统多孔不锈钢滤材相比，梯度孔径(非对称)型多孔不锈钢过滤通量大，压降小，反冲洗周期长，且反冲洗效果更好多孔不锈钢主要应用于石油化工、冶金、航空航天、生物制药、气流分布、能源、食品、环保、稳流等行业，如催化剂过梯度型滤、药液提纯、气体除尘、牛奶果汁净化浓缩等。此外，多孔不锈钢还常被用作陶瓷、分子筛、高分子等功能材料的载体。梯度型多孔不锈钢主要应用于石油化工、冶金、航空航天、生物制药、气流分布、能源、食品、环保、稳流等行业，如催化剂过滤、药液提纯、气体除尘、牛奶果汁净化浓缩等。此外，多孔不锈钢还常被用作陶瓷、分子筛、高分子等功能材料的载体。梯度多孔不锈钢主要应用于石油化工、冶金、航空航天、生物制药、气流分布、能源、食品、环保、稳流等行业，如催化剂过滤、药液提纯、气体除尘、牛奶果汁净化浓缩等。此外，多孔不锈钢还常被用作陶瓷、分子筛、高分子等功能材料的载体。我公司可按客户要求定制、研发各种多孔金属材料、器件与设备。特点：1、机械强度高、韧性好2、耐压性高，易于连接和密封3、稳定性好，抗热震性强4、孔径可控5、使用寿命长，经济效益高梯度型多孔不锈钢 由大孔支撑体和微孔膜层（厚50-500μm、孔径0.1-5μm）构成，解决了过滤精度和过滤阻力的矛盾多孔不锈钢主要应用于石油化工、冶金、航空航天、生物制药、气流分布、能源、食品、环保、稳流等行业，如催化剂过梯度型滤、药液提纯、气体除尘、牛奶果汁净化浓缩等。此外，多孔不锈钢还常被用作陶瓷、分子筛、高分子等功能材料的载体。 产品优势1、膜面光洁2、抗污染3、错流效果好4、易反洗5、还可用作载体材料多孔不锈钢主要应用于石油化工、冶金、航空航天、生物制药、气流分布、能源、食品、环保、稳流等行业，如催化剂过梯度型滤、药液提纯、气体除尘、牛奶果汁净化浓缩等。此外，多孔不锈钢还常被用作陶瓷、分子筛、高分子等功能材料的载体。

梯度混合螺圈订货号: 6.2758.000用于梯度混合材料：PEEK

产品信息：Thermo Scientific pH 梯度缓冲液简单开发电荷异构体表征方法Thermo Scientific pH 梯度缓冲液可以加快 QA/QC 的方法开发和方法转移。可使用传统的 LC 方法对多种蛋白和 MAb 的变异体进行电荷异构体的表征。*专利的缓冲液，使用于可以使用快速、可靠和重现性好的 pH 梯度方法进行分析，方法优化简单，易于自动化*即拆即用的 LC 色谱柱和系统，不需要进行繁琐的流动相的调整*适用于大多数 MAbs 订货信息：pH 梯度缓冲液订货信息描述部件号CX-1 pH 梯度缓冲液 A (pH 5.6), 125mL083273CX-1 pH 梯度缓冲液 B (pH 10.2), 125mL083275CX-1 pH 梯度缓冲液工具包 (pH 5.6 至 10.2), 125mL083274CX-1 pH 梯度缓冲液 A (pH 5.6), 250mL085346CX-1 pH 梯度缓冲液 B (pH 10.2), 250mL085348CX-1 pH 梯度缓冲液工具包 (pH 5.6 至 10.2), 250mL085349CX-1 pH 基本梯度工具包 (pH 5.6 至 10.2), 125mL083381CX-1 pH 快速梯度工具包 (pH 5.6 至 10.2), 125mL083378CX-1 pH 高分离度工具包 (pH 5.6 至 10.2), 125mL083272CX-1 pH 基本梯度平台 (pH 5.6 至 10.2), 125mL083380CX-1 pH 快速梯度 平台 (pH 5.6 至 10.2), 125mL083376CX-1 pH 高分离度平台 (pH 5.6 至 10.2), 125mL083270pH 设计软件085022

低压梯度混合器订货号: 6.2758.020

四元梯度比例阀用途介绍：用于替换六通比例阀性能特点：性能完全满足安捷伦1100，1200，1260和1290四元泵出厂标准梯度精度，优于0.5%；通过制药业的IQ，PQ和OQ测试寿命长，提供18个月质保；测试数据：图为珂睿比例阀用于安捷伦1100液相图为珂睿GPV在安捷伦1100液相上的梯度比例曲线图，梯度比例准确度为±0.5%此图为珂睿GPV在安捷伦1100液相上，以10%为梯度比例，GPV 3组通道的混合准确度实际值，均＜±0.5%由以上图和数据可以得出以下结论：珂睿GPV梯度比例准确，性能稳定可靠。比例阀细节图：

SHP-16二元高压梯度泵适用于高通量快速检测。具有更高的耐压，配合100Hz的采样频率和高精度进样器，可以充分提高分析效率，降低溶剂损耗，SHP-16二元高压梯度泵配合高性能比例阀能够实现准确的流量输出和梯度精度，稳定的压力控制可以将压力脉动控制在10psi以内，从而得到更优良的定性重复性，同时内置后冲洗组件可以清洗柱塞杆上残留的盐结晶，延长密封圈的使用寿命，有效控制维护费用。

SHP-18四元低压泵集成了在线脱气和后冲洗功能，节省空间、降低延迟体积、易于维护。内置后冲洗组件可以清洗柱塞杆上的盐结晶，延长密封圈使用寿命。更低的延迟体积，在梯度分析方法中能更快速准确的响应梯度变化。适用于药品方法开发、食品及环境样品分析等。

梯度混合螺圈Mixing coil for high pressure gradients订货号： 6.2758.000用于梯度混合技术参数材料PEEK

低压梯度混合器Mixing coil for low pressure gradients订货号： 6.2758.020

Nalgene 5100 冻存1℃冷冻容器，“梯度降温冻存盒”，聚碳酸酯冻存1℃冷冻容器，“梯度降温冻存盒”，聚碳酸酯；蓝色高密度聚乙烯盖；白色高密度聚乙烯管槽；泡沫衬垫为成功冷冻保存细胞提供精确和良好重复性的冷却率：-1℃ / 分钟。仅需要100% 的异丙醇和机械冷冻装置。标签上带有图示步骤说明。最多可容纳18 个管瓶。支架可防止管瓶与醇接触，以防由于芯吸作用而造成污染、弄掉标签或在管瓶上留下痕迹。装有醇的容器可在室温下存储，从而节约了冷冻空间。订货信息：Nalgene 5100 冻存1℃冷冻容器，“梯度降温冻存盒”，聚碳酸酯目录编号 5100-0001盖尺寸，mm120高度 × 直径，mm86×117高度 × 直径，in.3-7/16×4-5/8适用 Nalgene 冻存器具1.0. 1.2. 1.5 和 2.0 ml管瓶每箱数量1

梯度降温冻存盒把细胞放到程序降温盒内，把程序降温盒放到-80度的冰箱里，盒内温度就会成线性下降。保护细胞不被损伤。NALGENE 程序降温盒 或称 细胞冻存盒的材质MaterialsPolycarbonate 聚碳酸酯 blue high-density polyethylene closure 蓝色高密度聚乙烯盖 white high-density polyethylene vial holder 白色高密度聚乙烯管槽 foam insert 泡沫衬垫NALGENE 程序降温盒 或称 细胞冻存盒的参数盖子的直径： 120mm 高度X直径： 86X117mm 适用Nalgene冻存器具： 1mL/1.2mL/1.5mL/2mL管瓶聚碳酸酯；蓝色高密度聚乙烯盖；白色高密度聚乙烯管槽；泡沫衬垫为成功冷冻保存细胞提供精确和良好重复性的冷却率：-1℃/分钟。仅需要100%的异丙醇和机械冷冻装置。标签上带有图示步骤水明。最多可容纳18个管瓶。支架可防止管瓶与醇接触-以防由于芯吸作用而造成污染、弄掉标签或在管瓶上留下痕迹。装有醇的容器可在室温下存储，从而节约了冷冻空间。简单的装置可实现每分钟1℃的降温，可大大的提高细胞的存活率。用之前在盒夹层内装入100%异丙醇。可装18个冻存管。

氨基酸分析 (AccQ-Tag HPLC柱及消耗品)§ AccQ-Tag化学品套装所含产品能够满足您250次以上蛋白和肽水解物氨基酸分析所需产品描述规格/包装货号价格AccQ-Tag化学品包 (包括试剂包, 色谱柱, 洗脱液A×2, 样品衍生管×4, 氨基酸标准品, 用户指南)WAT05287525915AccQ-Fluor试剂包, 包括：AccQ-Fluor试剂1 AccQ-Fluor试剂2A AccQ-Fluor试剂2B5×6mL vials5×3mL vials5×4mL vialsWAT0528805826AccQ-Tag色谱柱3.9×150 mmWAT0528858533AccQ-Tag洗脱液A, 浓缩液1 literWAT0528902790AccQ-Tag洗脱液B (配用高压梯度泵)1 literWAT0528951103样品衍生管72 /pkWAT007571743氨基酸标准品, 水解物10×1 mL ampulesWAT0881221456AccQ-Tag用户指南1/pkWAT0528741456

影响医药中间体胶体磨研磨效果的因素其实很简单，医药中间体高速胶体磨，医药中间体湿法超微粉碎机，医药中间体湿磨机，医药高速纳米研磨机 ，化工原料高剪切胶体磨，原料药高速纳米胶体磨，头孢类抗生素纳米胶体磨 所谓医药中间体，实际上是一些用于药品合成工艺过程中的一些化工原料或化工产品。这种化工产品，不需要药品的生产许可证，在普通的化工厂即可生产，只要达到一些的别，即可用于药品的合成。 我国每年约需与化工配套的原料和中间体2000多种，需求量达250万吨以上。经过30多年的发展，我国医药生产所需的化工原料和中间体基本能够配套，只有少部分需要进口。而且由于我国资源比较丰富，原材料价格较低，有许多中间体实现了大量出口。那么，我国医药中间体域面临哪些发展机遇呢？我国β－内酰胺类抗生素经过近50年的发展，已经形成了完整的生产体系。2012年几乎所有的β－内酰胺类抗生素（除利期内的品种外）我国都能生产，而且成本很低，青霉素产量居位，大量出口供应国际市场；头孢类抗生素基本能够自给自足，还能争取一部分出口。2012年，与β－内酰胺类抗生素配套的中间体我国全部能够自己生产，除了半合成抗生素的母核7－ACA和7－ADCA需要部分进口外，所有的侧链中间体均可生产，而且大量出口。 以β－内酰胺类抗生素的主要配套中间体苯乙酸为例，我国现有苯乙酸生产厂家近30家，总年产能力约2万吨。但多数企业规模偏小，大的年产2000吨，其他大多年产数百吨。2003年国内苯乙酸总需求量约1.4万吨，消费结构为：青霉素G占85%，其他医药占4%，香料占7%，农药及其他域占4%。随着国内香料、医药、农药等行业的发展，苯乙酸需求量将进一步增加。预计到2005年，我国医药工业将消耗苯乙酸约1.4万吨，农药行业将消费500吨，香料行业约消费2000吨。再加上其他域的消费量，预计2005年国内苯乙酸总需求量将达1.8万吨。 所以上海依肯机械设备有限公司根据日益增长的市场需求结合多年来积累的丰富的行业经验以及成功案例特别推出医药中间体CMD2000系列胶体磨突破传统意义上的粉碎机，是技术上的进一步革新。好的粉碎效果源自硬质刀具的表面结构，三组分散刀头，表面含有不同粒度大小的金属颗粒，这保证了物料在通过各刀头后达到理想的细化效果。该锥体磨独特的锥形设计，增大了冷却表面积，更利于长时间工作。 产品说明：锥体磨CMD2000是CM2000的更进一步。通过减少颗粒粒度和湿磨，可获得更细悬浮液，技术更创新。这是通过将锥形刀具间的间隙调节至小来完成的。间隙可进行无调节。好的粉碎效果亦源于硬质刀具的表面结构。刀具表面含高质材料。 第1由具有精细度递升的三锯齿突起和凹槽。定子可以无限制的被调整到所需要的与转子之间的距离。在增强的流体湍流下，凹槽在每都可以改变方向。 第2由转定子组成。分散头的设计也很好地满足不同粘度的物质以及颗粒粒径的需要。在线式的定子和转子（乳化头）和批次式机器的工作头设计的不同主要是因为在对输送性的要求方面，特别要引起注意的是：在粗精度、中等精度、细精度和其他一些工作头类型之间的区别不光是转子齿的排列，还有一个很重要的区别是不同工作头的几何学特征不一样。狭槽数、狭槽宽度以及其他几何学特征都能改变定子和转子工作头的不同功能。根据以往的惯例，依据以的经验特制工作头来满足一个具体的应用。医药中间体CMD2000系列胶体磨（研磨分散机）的特点：① 线速度很高，剪切间隙非常小，当物料经过的时候，形成的摩擦力就比较剧烈，结果就是通常所说的湿磨② 定转子被制成圆椎形，具有精细度递升的三锯齿突起和凹槽。③ 定子可以无限制的被调整到所需要的与转子之间的距离④ 在增强的流体湍流下，凹槽在每都可以改变方向。⑤ 高质量的表面抛光和结构材料，可以满足不同行业的多种要求。医药中间体CMD2000系列胶体磨设备参数选型表高速胶体磨流量*输出线速度功率入口/出口连接类型l/hrpmm/skWCMD 2000/470014000404DN25/DN15CMD 2000/55,00010,5004011DN40/DN32CMD 2000/1010,0007,3004022DN50/DN50CMD 2000/2030,0004,9004045DN80/DN65CMD 2000/3060,0002,8504075DN150/DN125CMD 2000/501000002,00040160DN200/DN150*流量取决于设置的间隙和被处理物料的特性，同时流量可以被调节到大允许量的10%。影响医药中间体胶体磨研磨效果的因素其实很简单，医药中间体高速胶体磨，医药中间体湿法超微粉碎机，医药中间体湿磨机，医药高速纳米研磨机 ，化工原料高剪切胶体磨，原料药高速纳米胶体磨，头孢类抗生素纳米胶体磨

高速傅立叶变换红外光谱仪配件是顶级的红外光谱分析系统，用于识别分析有机材料,无机材料，是单光束光谱仪，具有极高的扫描速度快和精度，是用于工业，科学和质量控制领域的各种分析应用的重要工具。高速傅立叶变换红外光谱仪配件特点? 样品制备容易?可连接不同类型的配件以扩展功能，如采样卡；液体细胞；空气电池； ATR和其他? 维护简单?软件强大，?USB接口?样品室宽敞?CE认证?可选配件高速傅立叶变换红外光谱仪配件高稳定光学系统?组成光学平台的主要组件由铸铝加工而成。光学系统高度稳定，不需要调整，光程不需要维护。?精密机械，确保每个扫描的高度重复性。采用先进的设计理念设计光程和每个部件。? 系统的立体角反射光学系统，使操作简单，无需复杂的电子器件和额外的移动部件。此外，用户可更换光谱仪的许多组件，在仪器的使用寿命中节省时间。? 内部动态准直系统和可移动的反光镜驱动系统保持干涉仪的最佳状态。音圈驱动器和精密滑动，改善了系统在严峻条件下的工作的能力。? 光谱仪有一个干燥剂容器，干燥剂保护光束分离器等光学元件免受湿气破坏。高速傅立叶变换红外光谱仪FTIR7600软件包括下列功能： ?文件和编辑：打开，保存，打印，复制，粘贴，删除等和选项-自定义设置的光谱采集，显示，处理，保存和打印。?收集：配置测量参数（分辨率，平均值，范围...），实时显示不同模式和设置选项下的光谱结果，以及诊断组件的状态。?加工：光谱转换（A / T，日志，K-M...），光谱操作（删除，加，减，多道处理，规范...），和光谱校正。?分析：发现高峰期，贴标签，与库数据作比较，对光谱搜索定义设置，搜索库（选择库，添加新的库，制作，...），并显示结果。高速傅立叶变换红外光谱仪配件规格波数范围 7800 ~ 375 cm?1分辨率 1 cm?1信噪比 30000:1 （分辨率@4 cm-1；1分钟r扫描2100 cm?1以上)探测器 高性能 DLATGS分束器 涂层溴化钾光源 使用寿命长，稳定状态的红外发射器电子系统 24位A/D转换器 500 kHz, USB 2.0电源 110-220 V 交流电,，50-60 Hz尺寸大小 450 mm x 350 mm x 210 mm重量 14 kg

高速电光调制器由孚光精仪进口销售,孚光精仪是中国领先的进口（光学）精密仪器旗舰型服务商！精通光学，服务科学，先后为北京大学,中科院上海光机所，哈尔滨工业大学，中国工程物理研究院，,山东大学等单位提供这种高速普克尔盒。Felles1040KD*P系列高速电光调制器特意为高速激光快门和脉冲斩波的腔内和腔外应用而设计。这些高速光电调制器也常常用作Q开关、激光腔倒空器（cavity dumper）、偏振旋转器（Polarization rotator）。 这些高速电光调制器可以与大多数装置连接，因此具有广泛的的使用性。Felles1040KD*P系列高速光电调制器特别注意巧妙设计电容阻抗,使用低电感,全铜材料获取最小的RC 和 L/R时间常数,因此使得转换时间快到300皮秒(10mm孔径).该高速普克尔盒使用微型针直接连接印刷电路板驱动器和,N，BNC，HN，MHV, SHV型连接器,具有良好的连接普适性.Felles1040KD*P系列高速光调制器在同样孔径下具有最低的电容. 也有双晶体配置.1040系列高速电光调制器,高速光电调制器使用高质量的KD*P晶体作为电光介质.这些KD*P晶体没有应力,色心,裂纹,杂物,并且具有较低的双折射和波前畸变. 标准的产品为平整度:1/8波长, 平行度: 10 arcsec.高速电光调制器,高速光电调制器的窗口采用了无气泡和应力的高档熔炉石英窗口,光学质量高达 10-5 S/N.高速电光调制器产品参数: 型号：Felles1040孔径：10mm, 16mm材料：KD*P晶体 （98.5%+Deuterated D-KDP)承受峰值功率密度: (光束均匀无热点）750MW/cm^2 脉宽20ns10GW/cm^2 脉宽 500ps20GW/cm^2 脉宽100ps透光范围：400-1100nm透过率：98℅ 400-1064nm四分之一波电压： 2.1KV@694nm,1.1KV@694nm, 3.2KV@1064nm,1.7KV@1064nm任选消光比：700：1，800：1，1000：1@633nm 任选上升时间（10%-90%）：300ps,350ps,450ps,500ps任选电容：=6PF重量：0.18kg领先的进口精密激光光学器件旗舰型服务商--孚光精仪！

冻存1℃冻存容器，“降温盒”，聚碳酸酯；蓝色高密度聚乙烯盖；白色高密度聚乙烯管槽；泡沫衬垫 Cryo 1°C Freezing Container, "Mr. Frosty"特点： 可装 18 个冻存管，并具有 86 毫米盒高度（3-7/16 英寸），在冷却过程中节约了宝贵的冷冻空间螺旋盖在容器意外翻倒的情况下可保护内部样本避免使用不可靠的临时泡沫容器易于使用，只需要 高 异丙醇和机械冷冻设备 不接触酒精：无吸水、不影响标签、不弄花试管上的手写内容

掺锗熔融石英梯度折射率多模光纤，用于光波长850 nm和/或1300 nm的数据通信。金属化光纤配有24KT金或铝涂层。作为导电体，这些类型的涂层为用户提供了将光纤直接端接到涂层上的能力，从而支持密封组件。镀金和镀铝纤维能够承受极端温度和恶劣环境。这些光纤生产过程中使用的制造工艺导致低应力腐蚀敏感性，从而在最具挑战性的恶劣环境中使用时，为光纤提供更好的机械保护。所有金属涂层梯度折射率纤维均经过100%质量测试 工作波长800-1600nm纤芯直径62.5um通用参数特征 宽工作温度范围密封且可消毒可直接焊接真空引线和激光二极管引线抗辐射排气量低耐有机溶剂应用金属涂层梯度折射率光纤通常在极端条件下使用，例如： 高功率激光传输系统超高真空应用半导体制造辐射、腐蚀性和腐蚀性环境飞机、导弹、火箭、涡轮和喷气发动机监控材料疲劳传感应用Fiber name Wavelength纤芯直径[μm] ± 2 %包层直径[μm] ± 2 % Coating涂层直径[μm] ± 10 %GGI 50/125 IRMG 155VIS/IR 50125Gold155GGI 62.5/125 IRMG 155VIS/IR62.5125Gold155GGI 50/125 IRMA 175UV/VIS50125Alu175GGI 62.5/125 IRMA 175UV/VIS62.5125Alu175 注：GGI：锗分级指数。这些表中列出的项目是标准配置。其他配置可根据特殊要求提供。物理特性50/125/155 Gold62.5/125/155 Gold50/125/175 Alu62.5/125/175 Alu纤芯直径50 μm +/- 2 %62.5 μm +/- 2 %50 μm +/- 2 %62.5 μm +/- 2 % 核心非圆度：≤ 6 %≤ 6 %≤ 6 %≤ 6 %包层直径：125 μm +/- 2 %125 μm +/- 2 %125 μm +/- 2 %125 μm +/- 2 %包层不圆度：≤ 2 % ≤ 2 %≤ 2 %≤ 2 %涂层直径： 155 μm +/- 10 %155 μm +/- 10 %175 μm +/- 10 %175 μm +/- 10 %数值孔径：0.20 +/- 0.020.27 +/- 0.020.20 +/- 0.020.27+/- 0.02衰减 @ 850 nm:≤ 18 dB/km≤ 18 dB/km≤ 24 dB/km≤ 24 dB/km衰减 @ 1300 nm:≤ 16 dB/km≤ 16 dB/km≤ 20 dB/km ≤ 20 dB/km折射率 @ 850 nm:1.481 1.4911.4811.491折射率 @ 1300 nm:1.4761.4861.4761.486Bandwidth带宽 @ 850 nm:≥ 500 MHz.km≥ 160 MHz.km≥ 500 MHz.km≥ 160 MHz.kmMedian tensile strength:中值抗拉强度：≥ 3.3 GPa≥ 3.3 GPa≥ 5.3 GPa ≥ 5.3 GPaCorrosion parameter:腐蚀参数：≥ 50≥ 50≥ 100≥ 100Young’s modulus:杨氏模量：71.7 GPa71.7 GPa71.7 GPa71.7 GPa工作温度。范围：?269° C to 650° C?269° C to 650° C?269° C to 400° C?269° C to 400° C 短期弯曲半径：200x fiber radius200x fiber radius200x fiber radius200x fiber radius

西甲硅油乳剂高剪切均质机，西甲硅油高速胶体磨，一种西甲硅油乳剂均质乳化设备 西甲硅油，为液态二甲硅油的混合物，化学名称为α-（三甲基硅甲烷基）-ω-甲基聚[氧（二甲基亚硅烯基）]与二氧化硅复合物，是一种灰白色、乳白色粘稠液体的化学品，几乎不溶于水和甲醇，微溶于无水乙醇，与二氯甲烷、乙酸乙酯、丁酮和甲苯可部分混合。西甲硅油为胃肠病用药，临床上主要用于治疗由胃肠道中聚集了过多气体而引起的不适症状如腹胀等，术后也可使用，也可作为腹部影像学检查的辅助用药（例如：X-线、超声、胃镜检查）以及作为双重对比显示的造影剂悬液的添加剂。 西甲硅油为一种稳定的表面活性剂，即聚二甲基硅氧烷，可改变消化道中存在于食糜和黏液内气泡的表面张力，并使之分解，释放出的气体可被肠壁吸收或通过肠蠕动而排出。国内常单用二甲硅油或二氧化硅作为消泡剂，但作用较弱；两者合用，消泡作用增强，二甲硅油9.4mg，二氧化硅0.6mg，即能达到1000mg二甲硅油的功效。作为二甲硅油与二氧化硅的复合物，西甲油的药理作用远胜于二甲硅油或二氧化硅。西甲硅油属于药理学和生理学惰性物质，大鼠的亚急性毒性实验表明西甲硅油无毒性作用。 西甲硅油溶剂的功效和作用是如何的，日就来跟大伙儿介绍一下有关西甲硅油溶剂的事儿，很多父母需要亲身经历宝宝胀气的这一全过程，如何缓解宝宝胀气这一问题呢？下边就来跟大伙儿详解一下，西甲硅油溶剂的使用方法使用量。西甲硅油是一种稳定的表面活性剂,即聚二甲基硅氧烷,可改变消化道中存在于食糜和黏液内气泡的表面张力,并使之分解,释放出的气体可被肠壁吸收或通过肠蠕动而排出，是纯粹的物理性作用。西甲硅油用于治疗因胃肠道中聚集了过多气体而引起的不适症状:如腹胀等,术后胀气也可使用。还可作为腹部影像学检查的辅助用药以及作为双重对比显示的造影剂混悬液的添加剂。有文献报道，西甲硅油乳剂可用于新生儿胃肠功能紊乱的治疗；西甲硅油联合聚乙二醇4000治疗儿童便秘疗效佳；西甲硅油联合厚朴排气可有效减轻机械通气并发腹胀患者的临床症状和体征。 上海依肯机械有限公司特别推出高剪切乳化均质机ERS2000系列，ERS2000在线式高速高剪切乳化均质机，主要用于微乳液及超细悬浮液的生产。由于工作腔体内三组均质乳化头(定子+转子)同时工作，乳液经过高剪切后，液滴更细腻，粒径分布更窄，因而生成的混合液稳定性更好。三组均质乳化头均易于更换，适合不同的工艺应用。该系列中不同型号的机器都有相同的线速度和剪切率，非常易于扩大规模化生产。符合CIP/SIP清洁标准，适合食品及医药生产。 IKN高速高剪切均质乳化机选型表： 均质乳化机标准流量（H2O）输出转速标准线速度马达功率进出口尺寸 型号l/hrpmm/s kWERS 2000/4300-1,00014000402.2DN25/DN15ERS 2000/51,000-1.50010,500407.5DN40/DN32ERS 2000/103,0007,3004015DN50/DN50ERS 2000/208,0004,9004037DN80/DN65ERS 2000/3020,0002,8504075DN150/DN125 ERS 2000/5040,0002,00040160DN200/DN150西甲硅油乳剂高剪切均质机，西甲硅油高速胶体磨，一种西甲硅油乳剂均质乳化设备

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022

pH Gradient Buffer SolutionsRecombinant monoclonal antibodies (MAbs) can be highly heterogeneous due to modifications such as sialylation, deamidation and C-terminal lysine truncation. As biotherapeutic drugs are becoming more popular, chemists in biopharmaceutical laboratories are coming under increasing pressure to adopt a fast, generic, and robust approach to clone screening, method development, and subsequent method transfer to QA/QC.Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography. This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation. The building blocks of the pH gradient platform are two multicomponent zwitterionic buffer concentrates, prepared using a patent-pending formulation. Buffer A is titrated to pH 5.6 and Buffer B is titrated to pH 10.2. In this pH range, each buffer species is either neutral or negatively charged. Therefore, they will not be retained by the cation-exchange column stationary phase and will serve as good buffers for the mobile phase and the stationary phase. All that is required to generate a pH gradient is a 1:10 dilution of the pH buffer concentrates—then you’re ready to go! A linear pH gradient from pH 5.6 to 10.2 can simply be delivered by running a pump gradient from 100% eluent A to 100%eluent B.Thermo Scientific pH buffer concentrates used in the pH gradient platform can be purchased individually or as a pair, in quantities of 125 mL or 250 mL. For added convenience, the 125 mL buffers can also be bundled with columns in a number of specifically preconfigured kits.The CX-1 pH gradient starter kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 10 μm, 4 × 250 mm column.The CX-1 pH gradient high throughput kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 50 mm column.The CX-1 pH gradient highresolution kit contains 125 mL each of buffers A and B, plus a MAbPac SCX-10, 5 μm, 4 × 250 mm column.For the ultimate flexibility, the preconfigured kits are also available as platforms, including the pH Designer Software. The options are listed in the table below:pH Buffer ConcentratesCX-1 pH Gradient Buffer A (pH 5.6), 125 mL083273CX-1 pH Gradient Buffer B (pH 10.2), 125 mL083275CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 125 mL083274CX-1 pH Gradient Buffer A (pH 5.6), 250 mL085346CX-1 pH Gradient Buffer B (pH 10.2), 250 mL085348CX-1 pH Gradient Buffer Kit (pH 5.6 to 10.2), 250 mL085349CX-1 pH Gradient Starter Kit (pH 5.6 to 10.2), 125mL083381CX-1 pH Gradient High Throughput Kit (pH 5.6 to 10.2), 125 mL083378CX-1 pH Gradient High Resolution Kit (pH 5.6 to 10.2), 125 mL083272CX-1 pH Gradient Starter Platform (pH 5.6 to 10.2), 125 mL083380CX-1 pH Gradient High Throughput Platform (pH 5.6 to 10.2), 125 mL083376CX-1 pH Gradient High Resolution Platform (pH 5.6 to 10.2), 125 mL083270pH Designer Software085022