垂直扩散池
The vertical diffusion cell (VDC) system is a simple, reliable, and reproducible means of measuring drug release from semisolid (cream, ointment, and gel) dosage forms.The membrane, with its application side up, is placed in a VDC (typically a 15-mm diameter orifice), e.g., a Franz cell. The VDC assembly consists of two chambers (a donor chamber and a receptor chamber), separated by a donor compartment and held together by a clamp.This type of cell is commonly used for testing the in vitro release rate of topical drug products, cosmetics, skin-care products and ophthalmics.USP 1724 compliantCompatible Cells Part No.DescriptoinOEM RefPSVDC0904CP-HRClear Glass – Complete VDC cellVertical Diffusion Cell,Clear Glass, 9 mm Orifice, 4 mL vol, “Small”58-001-451PSVDC1507CP-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 7 mL vol, “Standard”Recommended by US FDA for topicals58-001-455PSVDC1512CP-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 12 mL vol, “Large”58-001-459PSVDC1520CP-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 20 mL vol, “Large”–PSVDC0904CO-HRClear Glass – VDC cell OnlyVertical Diffusion Cell, Clear Glass, 9 mm Orifice, 4 mL vol, “Small”58-001-453PSVDC1507CO-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 7 mL vol, “Standard”Recommended by US FDA for topicals58-001-457PSVDC1512CO-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 12 mL vol, “Large”58-001-461PSVDC1520CO-HRVertical Diffusion Cell, Clear Glass, 15 mm Orifice, 20 mL vol, “Large”– Part No.DescriptoinOEM RefPSVDC0904CP-AHRAmber Glass – Complete VDC cellVertical Diffusion Cell, Amber Glass, 9 mm Orifice, 4 mL vol, “Small”58-001-452PSVDC1507CP-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 7 mL vol, “Standard”58-001-456PSVDC1512CP-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 12 mL vol, “Large”58-001-460PSVDC1520CP-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 20 mL vol, “Large”–PSVDC0904CO-AHRAmber Glass – VDC cell OnlyVertical Diffusion Cell, Amber Glass, 9 mm Orifice, 4 mL vol, “Small”58-001-454PSVDC1507CO-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 7 mL vol, “Standard”58-001-458PSVDC1512CO-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 12 mL vol, “Large”58-001-462PSVDC1520CO-AHRVertical Diffusion Cell, Amber Glass, 15 mm Orifice, 20 mL vol, “Large”– VDC Parts Part No.DescriptoinOEM RefPSVDCGLDSK-HRGlass Disk, suited for all TDS cells58-001-506PSVDCCLRNG-HRCell ring58-001-507PSVDCDSW09-HRDosage wafer for 4ml cells, 9 mm orifice58-001-518PSVDCDSW15-HRDosage wafer for 7, 12, 20ml cells, 15 mm orifice58-001-511 PSVDCCLPAS-HRClamp Assembly for 4, 7, 12, 20ml cells58-001-450PSVDC0904CT-HRThreaded Cell Top, Clear Glass, 2ml volume suited for 4ml cell58-001-530PSVDC1507CT-HRThreaded Cell Top, Clear Glass, 6mll volume suited for 7, 12 and 20ml cell58-001-531PSVDCMSP06-HRStirrer Plate 6-position58-001-420PSVDCMC40-HRUniversal Speed control unit, 40 Watt, RS23258-001-425Permeation cell with isofill chamber was developed especially for automatic sampling, which can also pose a difficulty especially for the Franz Cell. Furthermore, this model can be used with labile skins such as separated epidermis or mucous membranes of all kinds. An additional problem for cells with horizontal application is the formation of air bubbles under the skin. Vertical application as well as the design of the permeation cell with isofill chamber can avoid this problem. Permeation area of the cell is approx. 65mm2. Part No.DescriptoinOEM RefPSKERSKI-01Permeation cellwith isofill chamber for liquides, approx. 10ml–PSKERSKI-02Permeation cell with isofill chamber for (semi)solid dosage forms, approx. 10 ml–PSKERSKI-03Permeation cell with isofill chamber for (semi)solid dosage forms, approx. 5 ml–PSKERSKI-04Permeation cell with isofill chamber for (semi)solid dosage forms, approx. 20 mlPSVDCMSP15-HRMagnetic Stirrer MixDrive 15 pos.–PSVDCMC40-HRUniversal Speed control unit, 40 Watt, RS232–
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