N-亚硝胺类化合物由于分析基体比较复杂，而且在样品中的含量比较低，一般分析都采用专属性的GC检测器进行分析，例如TEA或者NPD等。GCMSMS方法作为检测方法在专属性、灵敏度和价格比上都有一定的优势，所以本实验采用GCMSMS仪器对橡胶中的N-亚硝胺进行分析。其灵敏度、重现性和线性等都能满足实际测试的要求。

Triple quadrupole LC/MS systems have become widely accepted as a platform for targeted, large-batch, sample analysis on a day-to-day basis. A primary concern for routine/targeted analysis is instrument stability; which can vary over time due to the soiling of crucial ion optics components. While incorporating an internal standard and measuring abundance ratio may help alleviate signal drift from a data-analysis standpoint, it does not give key indications to the quality of the instrument’s health.