疫苗的冷冻干燥-在配方和工艺开发中的挑战和概念

2023/10/18   下载量: 0

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应用领域 制药/生物制药
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Vaccination prevents millions of deaths from infectious diseases per year; however, there are still millions of people who die from these diseases due to weak thermostability demanding cold chains, long-term stability issues and distribution challenges. All these limitations can be overcome by creating a dry product through lyophilization. With the urgency to develop a coronavirus vaccine, it is a crucial time to discuss the process of freeze-drying vaccines.

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Vaccination prevents millions of deaths from infectious diseases per year; however, there are still millions of people who die from these diseases due to weak thermostability demanding cold chains, long-term stability issues and distribution challenges. All these limitations can be overcome by creating a dry product through lyophilization. With the urgency to develop a coronavirus vaccine, it is a crucial time to discuss the process of freeze-drying vaccines.

Recently, Ms. Julia Kosan, a PhD candidate from Friedrich Alexander University, Erlangen, Germany presented a webinar that discussed the suitability of freeze-drying vaccines to increase their thermostability. This tech note summarizes the webinar and includes a selection of questions from the Q&A session.


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