重组小鼠白介素-1受体拮抗剂(Mouse IL-1RA)|10µg|CYT-658-上海希美化学有限公司

产品详情

IL 1RA Mouse
Interleukin-1 Receptor Antagonist Mouse Recombinant
Catalog No. CYT-658
Synonyms:
IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, F630041P17Rik.

Introduction:
Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Description:
IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa.
The IL1ra is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The protein was lyophilized from a concentrated (1mg/ml) solution in water containing NaHCO3.
Solubility:
It is recommended to reconstitute the lyophilized Interleukin-1ra in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized Interleukin 1ra although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-1ra should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 98.0% as determined by:
(a) Analysis by Gel Filtration.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first six N-terminal amino acids was determined and was found to be Ala-Cys-Arg-Pro-Ser-Gly.

Biological Activity:
The mouse IL-1Ra is capable of inhibiting IL-1-alpha activity in helper T cell line D10.G4.1.

Protein content:
Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280 nm using the absorbency value of 0.91 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
2. Analysis by RP-HPLC, using a standard solution of IL-1 ra as a Reference Standard.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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重组小鼠白介素-1受体拮抗剂(Mouse IL-1RA)由上海希美化学有限公司为您提供，货号CYT-658，规格：10µg，CAS号：，如您想了解更多关于重组小鼠白介素-1受体拮抗剂(Mouse IL-1RA)价格、重组小鼠白介素-1受体拮抗剂(Mouse IL-1RA)结构式、批发、用途等信息，欢迎咨询。除供应重组小鼠白介素-1受体拮抗剂(Mouse IL-1RA)外，还可为您提供重组猪白介素-1α(Porcine IL-1a)、重组人白介素-1受体拮抗剂(Human IL-1RA)、重组人白介素-1受体拮抗剂 His(IL-1RA)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

供货周期：	现货
品牌：	Prospect Biosystems
规格：	10µg
货号：	CYT-658
CAS号：