AE1 Phospho(pY21)(SLC4A1)antibody|100ul|3557-1-上海希美化学有限公司

产品详情

AE1 Phospho(pY21)(SLC4A1)antibody
Cat.#: 3557-1
Rabbit Monoclonal Antibody
Clone ID: EPR1424
Swiss Prot: P02730
Mol Weight: 100kDa
Size: 100ul

Description
The AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both cell types it mediates the electroneutral transport of chloride and bicarbonate ions across the lipid bilayer, and, in erythrocytes (1). AE1 is phosphorylated on Tyr8and Tyr21 by SYK. It has been suggested that, upon phosphorylation by p72syk, Tyr8, and Tyr21 act as docking sites for the SH2 domain of Lyn, which subsequently phosphorylates AE1 at additional secondary sites (2).

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:50,000 - 200,000

Species Reactivity
Human

Species cross-reactivity determined by WB analysis only

Products Data

Western blot analysis on red blood cell lysates using anti-Phospho-AE1 (pY21) RabMAb (cat. #3557-1). Cells were either (A) untreated (B) treated with pervanadate.

Specificity
A phospho specific peptide corresponding to residues surrounding tyrosine 21 of human AE1 was used as an immunogen. This antibody only detects AE1 phosphorylated at tyrosine 21.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
SLC4A1 antibody, AE1 antibody, BND3 antibody, CD233 antibody, DI antibody, EMPB3 antibody, EPB3 antibody, FR antibody, MGC116750 antibody, MGC116753 antibody, MGC126619 antibody, MGC126623 antibody, RTA1A antibody, SW antibody, WD antibody, WD1 antibody, WR antibody, Band 3 anion transport protein antibody, Solute carrier family 4 member 1 antibody

Description References
1. Sahr KE, et al. Genomics 24(3):491-501, 1994
2. Brunati AM, et al. Blood 96(4):1550-7, 2000

AE1 Phospho(pY21)(SLC4A1)antibody由上海希美化学有限公司为您提供，货号3557-1，规格：100ul，CAS号：，如您想了解更多关于AE1 Phospho(pY21)(SLC4A1)antibody价格、AE1 Phospho(pY21)(SLC4A1)antibody结构式、批发、用途等信息，欢迎咨询。除供应AE1 Phospho(pY21)(SLC4A1)antibody外，还可为您提供Recombinant Human SLC4A4、人过敏毒素/补体片断4(C4a)ELISA Kit、AE1 Phospho(pY359)(SLC4A1)antibody等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

Business information

工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：
规格：	100ul
货号：	3557-1
CAS号：