Mouse Anti Human FK506 Binding Protein 4 （FKBP4）

Mouse Anti Human FK506 Binding Protein 4 （FKBP4）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-390
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-390
Synonyms HBI, p52, Hsp56, FKBP52, FKBP59, PPIase, FKBP4, FK506-binding protein 4, Peptidyl-prolyl cis-trans isomerase, HSP-binding immunophilin, FKBP52 protein, 52 kDa FK506-binding protein, p59 protein.
Type Mouse Anti Human Monoclonal.
Introduction FKBP4 is part of the immunophilin protein family, which takes part in immunoregulation and necessary cellular processes concerning protein folding and trafficking. FKBP4 is a cis-trans prolyl isomerase that connects to the immunosuppressants FK506 and rapamycin. FKBP4 has high structural and functional similarity to FKBP1A, though, FKBP4 does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and is involved in immunoregulatory gene expression in B and T lymphocytes. FKBP4 is known to connect with phytanoyl-CoA alpha-hydroxylase. FKBP4 associates with HSP90 & HSP70 thus takes part in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. FKBP4 highly associates with adeno-associated virus type 2 vectors (AAV) resulting in a considerable increase in AAV-mediated transgene expression in human cell lines. FKBP4 is involved in the optimal use of AAV vectors in human gene therapy.
Clone PAT4D3AT.
Immunogen Anti-human FKBP4 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human FKBP4 amino acids 1-459 purified from E. coli.
Ig Subclass Mouse IgG2b heavy chain and κ light chain.
Purification Method FKBP4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications FKBP4 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000 ~ 1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Mouse Anti Human FK506 Binding Protein 4 （FKBP4）由上海希美化学有限公司为您提供，货号ANT-390，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human FK506 Binding Protein 4 （FKBP4）价格、Mouse Anti Human FK506 Binding Protein 4 （FKBP4）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human FK506 Binding Protein 4 （FKBP4）外，还可为您提供重组人FK506结合蛋白4(Human FKBP4)、Mouse Anti Human Casein Kinase 2 alpha （）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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