Recombinant Human Heat Shock Protein 47(HSP47)

Recombinant Human Heat Shock Protein 47(HSP47)

参考价：面议
供货周期： 一周
品牌： Prospect Biosystems
规格： 10µg
货号： HSP-047
CAS号：
上海希美化学有限公司
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SERPINH1 Human
Heat Shock 47kDa Human Recombinant
Catalog No. HSP-047

Synonyms:
HSP47, HSP-47, Colligin-1, CBP1, Collagen Binding Protein-1, Serpin Peptidase Inhibitor Clade-H memebr 1, Serpin H1, Collagen-binding protein, Colligin, 47 kDa heat shock protein, Rheumatoid arthritis-related antigen RA-A47, Arsenic-transactivated protein 3, AsTP3, Cell proliferation-inducing gene 14 protein, SERPINH1, CBP2, gp46, PIG14, PPROM, RA-A47, SERPINH2.

Introduction:
SERPINH1 is part of the serpin superfamily of serine proteinase inhibitors. SEPINH1 expression is induced by heat shock. HSP47 localizes to the endoplasmic reticulum lumen and binds collagen therefore it is a molecular chaperone which takes part in the maturation of collagen molecules, facilitating the folding and assembly of procollagen molecules, retaining unfolded molecules within the ER, and assisting the transport of correctly folded-molecules from the ER to Golgi apparatus. Autoantibodies to HSP47 protein have been found in rheumatoid arthritis. SERPINH1 binds specifically to collagen and acts as a chaperone in the biosynthetic pathway of collagen.

Description:
Recombinant Human HSP47 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 439 amino acids (18-417 a.a.) and having a molecular mass of 48.9 kDa.
HSP47 human recombinant is fused to 37 amino acid His Tag at N-terminus and purified by convential chromatogrpahy techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile filtered colorless solution.

Formulation:
The SERPINH1 protein solution (1mg/ml) contains 20mM Tris-HCl, pH-8 & 10% Glycerol.

Stability:
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity:
Greater than 90.0% as determined by SDS-PAGE.

Amino Acid Sequence:
RGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAA EVKKPAAAAA PGTAEKLSPK AATLAERSAG LAFSLYQAMA KDQAVENILV SPVVVASSLG LVSLGGKATT ASQAKAVLSA EQLRDEEVHA GLGELLRSLS NSTARNVTWK LGSRLYGPSS VSFADDFVRS SKQHYNCEHS KINFRDKRSA LQSINEWAAQ TTDGKLPEVT KDVERTDGAL LVNAMFFKPH WDEKFHHKMV DNRGFMVTRS YTVGVMMMHR TGLYNYYDDE KEKLQIVEMP LAHKLSSLII LMPHHVEPLE RLEKLLTKEQ LKIWMGKMQK KAVAISLPKG VVEVTHDLQK HLAGLGLTEA IDKNKADLSR MSGKKDLYLA SVFHATAFEL DTDGNPFDQD IYGREELRSP KLFYADHPFI FLVRDTQSGS LLFIGRLVRP KGDKMRDEL.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals

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Recombinant Human Heat Shock Protein 47(HSP47)由上海希美化学有限公司为您提供，货号HSP-047，规格：10µg，CAS号：，如您想了解更多关于Recombinant Human Heat Shock Protein 47(HSP47)价格、Recombinant Human Heat Shock Protein 47(HSP47)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Heat Shock Protein 47(HSP47)外，还可为您提供大鼠热休克蛋白47(HSP47)ELISA Kit、人硫酸乙酰肝素蛋白多糖2(HSPG2)ELISA Kit 等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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