重组大鼠白介素-15(Rat IL-15)|2μg/10μg/1mg|CYT-345-上海希美化学有限公司

产品详情

IL 15 Rat
Interleukin-15 Rat Recombinant
Catalog No. CYT-345
Synonyms:
IL-15, MGC9721.

Introduction:
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Description:
Interleukin-15 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 115 amino acids and having a molecular mass of 13533 Dalton.
The IL-15 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The protein was lyophilized from 10mM Tris, pH-8.5.

Solubility:
It is recommended to reconstitute the lyophilized Interleukin-15 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized Interleukin-15 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL15 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Asn-Trp-Ile-Asp.

Biological Activity:
The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be < 10 ng/ml, corresponding to a Specific Activity of 1 x 105 IU/mg.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» IL 15 Antibody
» IL 15 Human
» IL 15 Human His
» IL 15 Mouse
» IL 15 Mouse, His
» IL 15 Porcine

重组大鼠白介素-15(Rat IL-15)由上海希美化学有限公司为您提供，货号CYT-345，规格：2μg/10μg/1mg，CAS号：，如您想了解更多关于重组大鼠白介素-15(Rat IL-15)价格、重组大鼠白介素-15(Rat IL-15)结构式、批发、用途等信息，欢迎咨询。除供应重组大鼠白介素-15(Rat IL-15)外，还可为您提供重组人白介素-15(Human IL-15)、重组人白介素-15 His(Human IL-15 His)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	Prospect Biosystems
规格：	2μg/10μg/1mg
货号：	CYT-345
CAS号：