Recombinant Human Trefoil Factor-3(Human TFF3)

Recombinant Human Trefoil Factor-3(Human TFF3)

参考价：面议
供货周期： 一周
品牌： Prospect Biosystems
规格： 5μg/20μg/1mg
货号： CYT-616
CAS号：
上海希美化学有限公司
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TFF3 Human
Trefoil Factor-3 Human Recombinant
Catalog No. CYT-616

Synonyms:
TFF-3, ITF, TFI, HITF, hP1.B, TFF3, Trefoil factor 3, Intestinal trefoil factor.

Introduction:
Proteins of the TFF family are characterized by obtaining a minimum of 1 copy of the trefoil motif, a 40-amino acid domain that contains 3 conserved disulfides. Trefoil Factors are stable secretory proteins expressed in gastrointestinal mucosa which protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium.TFF2 inhibits gastric acid motility & secretion. TFF2 stabilizes glycoproteins in the mucus gel through interactions with carbohydrate side chains. TFF3 induces ciliogenesis and promotes airway epithelial ciliated cell differentiation, relatively through an epidermal growth factor receptor-dependent pathway. TFF3 overexpression is crucial for progression in mouse and human hepatocellular carcinogenesis. TFF-3 is normally expressed in hepatocellular carcinoma and its expression associates with tumor grade.

Description:
TFF3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids (22-80 a.a.) which includes a 10 amino acid His Tag fused at N-terminus and having a total molecular mass of 7.82 kDa.
TFF3 Human Recombinant is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
White lyophilized (freeze-dried) powder.

Formulation:
The TFF3 protein was lyophilized from 0.4μm filtered solution at a concentration of 0.5mg/mL containing 20mM Tris pH-7.5 and 150mM NaCl.

Solubility:
Add deionized water to a working concentration approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture.

Stability:
Lyophilized TFF3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TFF3 should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as by SDS-PAGE.

Amino acid sequence:
MKHHHHHHAS EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» TFF1 Human
» TFF1 Human, His
» TFF2 Human
» TFF2 Human, His

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Recombinant Human Trefoil Factor-3(Human TFF3)由上海希美化学有限公司为您提供，货号CYT-616，规格：5μg/20μg/1mg，CAS号：，如您想了解更多关于Recombinant Human Trefoil Factor-3(Human TFF3)价格、Recombinant Human Trefoil Factor-3(Human TFF3)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Trefoil Factor-3(Human TFF3)外，还可为您提供Recombinant Human Trefoil Factor-1(Human TFF1)、Recombinant Human Trefoil Factor-1 His Tag(Human TFF1 His)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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