Recombinant Mouse BID GST|2μg/10μg/1mg|PRO-643-上海希美化学有限公司

产品详情

BID Mouse, GST
BH3 Interacting Domain Death Agonist Mouse Recombinant, GST
Catalog No. PRO-643

Synonyms:
BH3-interacting domain death agonist, p22 BID, BID, FP497, MGC15319, MGC42355.

Introduction:
BID is a pro-apoptotic Bcl-2 protein having only the BH3 domain. In reaction to apoptotic signaling, BID interacts with another Bcl-2 family of cell death regulators, called Bax, they form a heterodimer resulting to the insertion of Bax into the outer mitochondrial membrane. Bax induces the opening of the mitochondrial voltage-dependent anion channel which lead to the release of cytochrome c and other pro-apoptotic factors from the mitochondria resulting in activation of caspases. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. The major proteolytic product p15 BID releasea cytochrome c. Isoform 1, Isoform 2 and Isoform 4 induce ice-like proteases and apoptosis while Isoform 3 does not induce apoptosis.

Description:
BID Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 1-195 amino acids and having a molecular mass of 48 kDa.
The Mouse BID is expressed as GST-Tag fusion protein and purified by proprietary chromatographic technique.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless liquid formulation.

Formulation:
The Mouse GST tag BID protein solution contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.

Stability:
GST BID although stable at 15°C for 1 week, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» BID Human
» BID Mouse
» tBID Mouse

Recombinant Mouse BID GST由上海希美化学有限公司为您提供，货号PRO-643，规格：2μg/10μg/1mg，CAS号：，如您想了解更多关于Recombinant Mouse BID GST价格、Recombinant Mouse BID GST结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Mouse BID GST外，还可为您提供小鼠BH3结构域凋亡诱导蛋白(Bid)ELISA Kit、Recombinant Human BH3 Interacting Domain Death Agonist(BID)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

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工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：	Prospect Biosystems
规格：	2μg/10μg/1mg
货号：	PRO-643
CAS号：