化药新药研发其他>方法开发检测 | 通过Biotage微波合成仪以5-胺基吡唑，醛和丙酮为原料进行多组分合成吡唑并吡啶及其相关衍生物by耐士科技-上海鑫欣生物科技有限公司

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应用领域	化药/中药/生物制药
检测样本	化药新药研发
检测项目	其他>方法开发
参考标准	GB/T 8****

Abstract—The reactions of 3-substituted 5-aminopyrazoles with arylidenepyruvic acids and their synthetic precursors, pyruvic acid and aromatic aldehydes, were studied. Several different reaction pathways for these cyclocondensation reactions were established depending on the reaction conditions and building block selection. The formation of pyrazolo[3,4-b]pyridine-6-carboxylic acids as major products and related compounds was discussed from the mechanistic point of view.

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