null检测 | 软骨细胞中提取RNA 骨关节炎软骨细胞衰老研究-上海漾盟仪器有限公司

方案摘要

方案下载

应用领域
检测样本
检测项目
参考标准

Replicative senescence occurs when normal somatic cells stop dividing. Senescent cells remain viable, but show alterations in phenotype, e.g. altered expression of matrix metalloproteinases ( MMPs ); these enzymes are known to be involved in cartilage destruction. It is assumed that cells deplete their replicative potential during aging, and age is a major risk factor for osteoarthritis (OA). Therefore, we hypothesized that chondrocytes in aging or diseased cartilage become senescent with associated phenotypic changes contributing to development or progression of OA.

方案下载

上一篇 Preparation of ultra®ne TiC±Ni cermet powders

下一篇用SPEX冷冻研磨机从软骨组织提取RNA

文献贡献者