Anti-Epac2抗体,鸟嘌呤核苷酸交换因子4抗体

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【产品名称】：Anti-Epac2抗体,鸟嘌呤核苷酸交换因子4抗体

【产品编号】：BYK-10955R

【规    格】：0.1ml/0.2ml

【相关标记】：Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记 

【浓    度】：1mg/1ml

【抗体来源】：Rabbit or Mouse or Goat

【克隆类型】：polyclonal or monoclonal

【产品类型】：一抗

【性    状】：Lyophilized or Liquid 

【亚    型】：IgG

【纯化方法】：affinity purified by Protein A

【储 存 液】：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

【产品应用】：not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Anti-Epac2抗体,鸟嘌呤核苷酸交换因子4抗体【产品别名】：CAMP GEFII; cAMP regulated guanine nucleotide exchange factor II; cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; CAMPGEFII; CGEF 2; CGEF2; Epac 2; EPAC2; Exchange factor directly activated by cAMP 2; Exchange protein directly activated by cAMP 2; Nbla00496; Putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; RAP guanine nucleotide exchange factor 4; RAPGEF 4; RAPGEF4; RPGF4_HUMAN.

【产品介绍】：3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac1 (cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the ras family GTPases Rap1 and Rap2 by promoting GTP binding in a cAMP-dependent manner (1,2). Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission (3). Human EPAC2 contains at least 31 exons and maps to chromosome 2q31 (4). The 4.4-kb Epac2 transcript is prominent in brain and adrenal gland (5,6). Within the brain, expression is strong in cortex, occipital pole, frontal lobe, temporal lobe, amygdala, putamen, hippocampus and cerebellum (5,6).

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【保存条件】：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

连续使用时4°C存储，保质期六个月补体C1qα链多肽抗体长期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。