英文名称 Anti-E2F8
中文名称 转录因子E2F8抗体
别 名 E2F 8; E2F family member 82; E2F transcription factor 8; E2F-8; E2f8; E2F8_HUMAN; FLJ23311; Transcription factor E2F8.
转录因子E2F8抗体浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 免疫学 染色质和核信号 信号转导 转录调节因子 新陈代谢 表观遗传学
蛋白分子量 predicted molecular weight: 94kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human E2F8 (285-326aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
Function : Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
Subunit : Forms heterodimers with E2F7 and, to a lesser extent, homodimers. Dimerization is important for DNA binding.
Subcellular Location : Nucleus.
Similarity : Belongs to the E2F/DP family
Database links : UniProtKB/Swiss-Prot: A0AVK6.1
半个多世纪以来，抗体一直作为常用的研究工具，因此对其使用和储存已有丰富的经验。这些经验让人们知道如何对抗体进行操作，由于抗体的稳定性好，使用并不困难。抗体较其他蛋白不易变性，易于存放、纯化和标记。蛋白G和蛋白A等抗体结合蛋白的发现使得这项工作更具可行性。
选择合适的抗体对免疫化学技术的成功极为重要。没有任何一种来源的抗体能够满足本书所述的各种方法的要求。为了研究某一重要的抗原，应选用具有不同特性的多种抗体。在没有一套良好特性的抗体可用于研究机体中每一种蛋白之前，选择及制备适合各种技术要求的抗体非常必要。
J11903 蛋白激酶Cη(PKCη)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Protein Kinase C Eta (PKCh) 48T/96T Rattus norvegicus (Rat)
J11904 Ⅰ型前胶原氨基端原肽(PⅠNP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Procollagen I N-Terminal Propeptide (PINP) 48T/96T Mus musculus (Mouse)
J11905 芳香酶(ARO)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Aromatase (ARO) 48T/96T Homo sapiens (Human)
J11906 组蛋白H2A(H2A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H2A (H2A) 48T/96T Bos taurus; Bovine (Cattle)
J11907 组蛋白H2A(H2A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H2A (H2A) 48T/96T Chicken (Gallus)
J11908 组蛋白H2A(H2A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H2A (H2A) 48T/96T Mus musculus (Mouse)
J11909 组蛋白H2A(H2A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H2A (H2A) 48T/96T Rattus norvegicus (Rat)
J11910 组蛋白H2A(H2A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H2A (H2A) 48T/96T Rhesus monkey (Simian)
J11911 Ⅱ型前胶原氨基端原肽(PⅡNT)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Procollagen II N-Terminal Propeptide (PIINP) 48T/96T Bos taurus; Bovine (Cattle)
J11912 Ⅱ型前胶原氨基端原肽(PⅡNT)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Procollagen II N-Terminal Propeptide (PIINP) 48T/96T Equus caballus; Equine (Horse)
J11913 组蛋白H3(H3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H3 (H3) 48T/96T Bos taurus; Bovine (Cattle)
J11914 组蛋白H3(H3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H3 (H3) 48T/96T Chicken (Gallus)
J11915 组蛋白H3(H3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H3 (H3) 48T/96T Sus scrofa; Porcine (Pig)
J11916 组蛋白H3(H3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H3 (H3) 48T/96T Rattus norvegicus (Rat)
J11917 组蛋白H3(H3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Histone H3 (H3) 48T/96T Oryctolagus cuniculus (Rabbit)
J11918 半乳凝素8(GAL8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 8 (GAL8) 48T/96T Bos taurus; Bovine (Cattle)
J11919 半乳凝素8(GAL8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 8 (GAL8) 48T/96T Homo sapiens (Human)
J11920 半乳凝素8(GAL8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 8 (GAL8) 48T/96T Mus musculus (Mouse)
J11921 半乳凝素8(GAL8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 8 (GAL8) 48T/96T Sus scrofa; Porcine (Pig)
J11922 半乳凝素8(GAL8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 8 (GAL8) 48T/96T Rattus norvegicus (Rat)
J11923 胰蛋白酶(TRY)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Trypsin (TRY) 48T/96T Sus scrofa; Porcine (Pig)
J11924 双肾上腺皮质激素(DCX)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Doublecortin (DCX) 48T/96T Homo sapiens (Human)
J11925 Ⅲ型胶原α1(COL3α1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Collagen Type III Alpha 1 (COL3a1) 48T/96T Homo sapiens (Human)
J11926 半乳凝素12(GAL12)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 12 (GAL12) 48T/96T Homo sapiens (Human)
J11927 半乳凝素12(GAL12)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 12 (GAL12) 48T/96T Mus musculus (Mouse)
J11928 半乳凝素6(GAL6)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 6 (GAL6) 48T/96T Mus musculus (Mouse)
J11929 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Bos taurus; Bovine (Cattle)
J11930 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Capra hircus; Caprine (Goat)
J11931 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Homo sapiens (Human)
J11932 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Mus musculus (Mouse)
J11933 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Sus scrofa; Porcine (Pig)
J11934 半乳凝素1(GAL1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 1 (GAL1) 48T/96T Rattus norvegicus (Rat)
J11935 基质金属蛋白酶15(MMP15)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Matrix Metalloproteinase 15 (MMP15) 48T/96T Homo sapiens (Human)
J11936 基质金属蛋白酶15(MMP15)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Matrix Metalloproteinase 15 (MMP15) 48T/96T Mus musculus (Mouse)
J11937 基质金属蛋白酶15(MMP15)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Matrix Metalloproteinase 15 (MMP15) 48T/96T Sus scrofa; Porcine (Pig)
J11938 S100钙结合蛋白(S100)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for S100 Calcium Binding Protein (S100) 48T/96T Homo sapiens (Human)
J11939 角蛋白1(KRT1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Keratin 1 (KRT1) 48T/96T Homo sapiens (Human)
J11940 胰岛素降解酶(IDE)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Insulin Degrading Enzyme (IDE) 48T/96T Homo sapiens (Human)
J11941 Lacritin蛋白(LACRT)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lacritin (LACRT) 48T/96T Homo sapiens (Human)
J11942 皮敌菌素(DCD)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Dermcidin (DCD) 48T/96T Homo sapiens (Human)
J11943 半乳凝素14(GAL14)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 14 (GAL14) 48T/96T Capra hircus; Caprine (Goat)
J11944 半乳凝素14(GAL14)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 14 (GAL14) 48T/96T Homo sapiens (Human)
J11945 半乳凝素14(GAL14)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Galectin 14 (GAL14) 48T/96T Rhesus monkey (Simian)
J11946 肾足蛋白(NPHN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Nephrin (NPHN) 48T/96T Mus musculus (Mouse)
J11947 肌钙蛋白T(TNT)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Troponin T (TNT) 48T/96T Sus scrofa; Porcine (Pig)
J11948 α-胞衬蛋白(SPTAN1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Alpha-Fodrin (SPTAN1) 48T/96T Chicken (Gallus)
J11949 谷氨酸脱氢酶(GDH)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutamate Dehydrogenase 1 (GDH) 48T/96T Bos taurus; Bovine (Cattle)
J11950 谷氨酸脱氢酶(GDH)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutamate Dehydrogenase 1 (GDH) 48T/96T Mus musculus (Mouse)
J11951 谷氨酸脱氢酶(GDH)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutamate Dehydrogenase 1 (GDH) 48T/96T Rattus norvegicus (Rat)
J11952 谷胱甘肽过氧化酶1(GPX1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione Peroxidase 1 (GPX1) 48T/96T Bos taurus; Bovine (Cattle)
J11953 谷胱甘肽过氧化酶1(GPX1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione Peroxidase 1 (GPX1) 48T/96T Sus scrofa; Porcine (Pig)
J11954 谷胱甘肽过氧化酶1(GPX1)转录因子E2F8抗体检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione Peroxidase 1 (GPX1) 48T/96T Oryctolagus cuniculus (Rabbit)
J11955 乳过氧化物酶(LPO)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lactoperoxidase (LPO) 48T/96T Bos taurus; Bovine (Cattle)
J11956 乳过氧化物酶(LPO)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lactoperoxidase (LPO) 48T/96T Capra hircus; Caprine (Goat)
J11957 弹性蛋白(ELN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Elastin (ELN) 48T/96T Rattus norvegicus (Rat)
J11958 血管生成素1(ANGPT1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Angiopoietin 1 (ANGPT1) 48T/96T Bos taurus; Bovine (Cattle)
J11959 血管生成素1(ANGPT1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Angiopoietin 1 (ANGPT1) 48T/96T Chicken (Gallus)
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