英文名称 Anti-ANKHD1
中文名称 艾滋病病毒制约锚定蛋白抗体
别 名 ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protein; hMASK; MASK; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain homolog; VBARP.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
艾滋病病毒制约锚定蛋白抗体交叉反应 Human, Dog, Pig, Cow, Horse, Sheep
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 细菌及病毒 细胞粘附分子
蛋白分子量 predicted molecular weight: 269kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ANKHD1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
艾滋病病毒制约锚定蛋白抗体产品介绍 May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Function : May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Subunit : Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR.
Subcellular Location : Cytoplasm.
Tissue Specificity : Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain.
Similarity : Belongs to the mask family.
Contains 25 ANK repeats.
Contains 1 KH domain.
Database links : UniProtKB/Swiss-Prot: Q8IWZ3.1
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