英文名称 Anti-Adrenodoxin/FDX
中文名称 肾上腺皮质线粒体铁氧还蛋白抗体
别 名 Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Sheep
肾上腺皮质线粒体铁氧还蛋白抗体产品类型 一抗
研究领域 肿瘤 细胞生物 神经生物学 信号转导 生长因子和激素 线粒体
蛋白分子量 predicted molecular weight: 13.5kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX (51-150aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肾上腺皮质线粒体铁氧还蛋白抗体产品介绍 Adrenodoxin (Adx) is an acidic [2Fe-2S] adrenal ferredoxin that belongs to the vertebrate ferredoxin family. ADX functions as a soluble electron carrier between the NADPH-dependent adrenodoxin reductase and cytochrome P450. ADX localizes to the adrenal cortex mitochondrial matrix, where it participates in the synthesis of Vitamin D and bile acids. Human ADX maps to chromosome 11q13.
Function : Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.
Subcellular Location : Mitochondrion matrix.
Tissue Specificity : Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Similarity : Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.
Database links : UniProtKB/Swiss-Prot: P10109.1
工商信息
信息已认证
