英文名称 Anti-ALS2CR3
中文名称 肌萎缩侧索硬化症相关蛋白3抗体
别 名 ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep
产品类型 一抗
研究领域 细胞生物 神经生物学 Alzheimer's
蛋白分子量 predicted molecular weight: 101kDa
性 状 Lyophilized or Liquid
肌萎缩侧索硬化症相关蛋白3抗体免 疫 原 KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌萎缩侧索硬化症相关蛋白3抗体产品介绍 ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Function : May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR
Subunit : Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.
Subcellular Location : Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner
Tissue Specificity : Widely expressed, with highest expression in heart.
Post-translational modifications : O-glycosylated
Similarity : Contains 1 HAP1 N-terminal domain.
Database links : UniProtKB/Swiss-Prot: O60296.2
工商信息
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