浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 肿瘤 肿瘤细胞生物标志物
蛋白分子量 predicted molecular weight: 93kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human DEPDC1 (606-660aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期调控蛋白SDP35抗体产品介绍
Function : May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Subunit : Isoform 2 and isoform 5 can form homodimers and heterodimers. Interacts with ZNF224.
Subcellular Location : Nucleus. Note=Co-localizes with ZNF224 at the nucleus.
Tissue Specificity : Expressed in testis. Up-regulated in bladder cancer cells (at protein level).
Similarity : Contains 1 DEP domain.
Contains 1 Rho-GAP domain.
工商信息
信息已认证
