浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse
产品类型 一抗
研究领域 细胞生物 信号转导 转录调节因子 结合蛋白 细胞骨架
蛋白分子量 predicted molecular weight: 342kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Cadherin 19
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘蛋白16抗体产品介绍 The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. DCHS1 (dachsous 1), also known as CDH19, CDH25, FIB1, KIAA1773 or PCDH16, is a 3,298 amino acid single-pass type I membrane protein that contains 27 cadherin domains and belongs to the cadherin superfamily. Expressed specifically in fibroblasts, DCHS1 functions as a Ca2+-dependent cell-cell (specifically fibroblast-fibroblast) adhesion protein that may be involved in wound healing. The gene encoding DCHS1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Subcellular Location : Cell membrane.
Tissue Specificity : Fibroblast specific.
Similarity : Contains 27 cadherin domains.
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