DNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶）

DNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶）英文名称  Anti-DFFB 

中文名称  DNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶） 

别    名  CAD; Caldesmon; Caspase activated deoxyribonuclease; Caspase activated DNase; Caspase activated nuclease; CDM; CPAN; Deoxyribonuclease III, caspase activated; DFF 40; DFF2; DFF40; Didff; DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 Da, beta polypeptide (caspase activated DNase); DNA fragmentation factor, 40 kD beta subunit; DNA fragmentation factor, 40 kD, beta polypeptide; DNA fragmentation factor, 40kDa, beta polypeptide (caspase activated DNase); DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNAation factor, beta subunit; DFFB_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg          

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Rabbit   

产品类型  一抗    

研究领域  细胞生物 细胞凋亡 细胞周期蛋白 激酶和磷酸酶 表观遗传学  

蛋白分子量  predicted molecular weight: 39kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human DFFB 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

DNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶）产品介绍 Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units.

Function : Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. 

Subunit : Heterodimer of DFFA and DFFB. Interacts with HIST1H1A. 

Subcellular Location : Cytoplasm. Nucleus.

Similarity : Contains 1 CIDE-N domain. 

Database links : UniProtKB/Swiss-Prot: O76075.1