Caspase 激活的脱氧核糖核酸酶抗体|0.2ml/200μg |-上海基免实业有限公司

产品详情

Caspase 激活的脱氧核糖核酸酶抗体英文名称 Anti-DFF-40beta/CAD/CPAN

中文名称 Caspase 激活的脱氧核糖核酸酶抗体

别名 DFF-40β; DFF40β; Caspase-activated deoxyribonuclease; DNA fragmentation factor, beta subunit; DNA fragmentation factor, beta polypeptide; caspase-activated DNase; DNA fragmentation factor 40 kDa subunit; DFF-40.

公司Caspase 激活的脱氧核糖核酸酶抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Mouse, Rat, Rabbit, Guinea Pig

产品类型一抗

研究领域细胞生物染色质和核信号细胞凋亡转录调节因子

蛋白分子量 predicted molecular weight: 40kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from mouse DFF-40 beta (201-260aa)

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase 激活的脱氧核糖核酸酶抗体产品介绍 Carbamoyl phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (CAD) is a multifunctional protein that initiates and regulates mammalian de novo pyrimidine biosynthesis. This trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis is the rate-limiting step in the de novo pyrimidine synthetic pathway. Although most of the CAD protein in the cell is cytosolic, phosphorylation at threonine 456 localizes the protein to the nucleus. While MAPK and EGF phosphorylate CAD at threonine 456, MAPK and c-myc have been found to induce over-expression of CAD.

Function : Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.

Subunit : Heterodimer of DFFA and DFFB

Subcellular Location : Cytoplasm. Nucleus.

Similarity : Contains 1 CIDE-N domain.

Database links : UniProtKB/Swiss-Prot: O54788.1

【存储要求】连续使用时4°C存储，保质期六个月；Caspase 激活的脱氧核糖核酸酶抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学

供货周期：	一周
品牌：	Abcam
规格：	0.2ml/200μg
货号：
CAS号：