产品详情
磷酸化膀胱癌缺失基因1抗体英文名称 Anti-Phospho-DBC1 (Tyr454)
中文名称 磷酸化膀胱癌缺失基因1抗体
别 名 DBC 1; DBC.1; DBCCR1; Deleted in bladder cancer chromosome region candidate 1; Deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; KIAA1967; OTTHUMP00000022751; p30 DBC; p30 DBC protein; Protein FAM5A.
公司磷酸化膀胱癌缺失基因1抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat
产品类型 一抗 磷酸化抗体
研究领域 肿瘤
蛋白分子量 predicted molecular weight: 103kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human DBC1 around the phosphorylation site of Tyr454
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化膀胱癌缺失基因1抗体产品介绍 The DBC1 (Deleted in breast cancer 1) amino terminus binds directly to the estrogen receptor alpha (ERalpha) hormone-binding domain in a strict ligand-independent manner. It may function in the modulation of ERalpha expression and hormone-independent breast cancer cell survival. It is ubiquitously expressed in normal tissues. DBC1 promotes p53-mediated apoptosis through specific inhibition of SIRT1.
【存储要求】连续使用时4°C存储，保质期六个月；磷酸化膀胱癌缺失基因1抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。
实验的用途：
1）WB：Western Blotting 免疫印迹
2）IH：Immunohistochemistry 免疫组化
3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)
4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)
5）IC：Immunocytochemistry 免疫细胞化学
工商信息
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