浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, ,G
产品类型 一抗
研究领域 肿瘤 细胞类型标志物 b-淋巴细胞
蛋白分子量 predicted molecular weight: 195kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human DEC-205
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
淋巴细胞抗原75抗体产品介绍 Ly75 is expressed in spleen, thymus, colon and peripheral blood lymphocytes and causes reduced proliferation of B-lymphocytes as well as acting as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Ly75 is also detected in myeloid and B lymphoid cell lines and isoforms 2 and 3 are expressed in Hodgkin and Reed-Sternberg (HRS) cells (malignant Hodgkin lymphoma cells).
Function : Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
Subcellular Location : Membrane; Single-pass type I membrane protein (By similarity).
Tissue Specificity : Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Post-translational modifications : N-glycosylated.
Similarity : Contains 10 C-type lectin domains.
Contains 1 fibronectin type-II domain.
Contains 1 ricin B-type lectin domain.
Database links : UniProtKB/Swiss-Prot: O60449.3
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