CD41抗体，abcam新抗

上海瑞齐生物技术有限公司

2014/09/06 11:19

Mouse Anti-CD41抗体，abcam新抗 antibody

ABCAM
Catalog Number : RS-2636R

Quantity size : 0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )

background:
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Specificity : · anti-CD41 is a mouse Polyclonal antibody, unconjugated

· specific for anti-CD41 of human, mouse and rat.

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt：125 kDa

Application :
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

Storage: Store at –CD41抗体，abcam新抗20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 oC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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