供货周期: | 一周 |
品牌: | 爱必信 |
规格: | >98% |
货号: | abs811387 |
CAS号: | 1234015-52-1 |
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抑制剂描述: 产品名称:LY2606368 产品别名:见爱必信官网 英文别名:LY2606368 靶点:Chk CAS:1234015-52-1 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述: LY2606368 is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. 溶解性:DMSO: ≥ 60 mg/mL 体外研究: 体内研究:LY2606368 (15 mg/kg, s.c.) significantly inhibits tumor growth in xenograft tumor models with less animal weight loss. LY2606368 (2 mg/kg, s.c.) and BMN673 combination has synergistic anticancer effect in gastric cancer PDX model, and the effect is higher than that of one drug alone.
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