供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs821932 |
CAS号: | 313526-24-8 |
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抑制剂描述: 产品名称:IBR2 产品别名:见爱必信官网 英文别名:IBR2 靶点:RAD51 CAS:313526-24-8 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:IBR2 is a specific RAD51 inhibitor. 溶解性: 体外研究: IBR2 shows interesting RAD51 inhibition activities. RAD51 is rapidly degraded in IBR2-treated cancer cells, and the homologous recombination repair is impaired, subsequently leading to cell death. The IC50 values of the original IBR2 are in the range of 12-20 μM for most tested cancer cell lines. IBR2 can inhibit the growth of triple-negative human breast cancer cell line MBA-MD-468 with an IC50 of 14.8 μM. 体内研究:IBR2 shows interesting RAD51 inhibition activities. RAD51 is rapidly degraded in IBR2-treated cancer cells, and the homologous recombination repair is impaired, subsequently leading to cell death. The IC50 values of the original IBR2 are in the range of 12-20 μM for most tested cancer cell lines. IBR2 can inhibit the growth of triple-negative human breast cancer cell line MBA-MD-468 with an IC50 of 14.8 μM.
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