供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 98% |
货号: | abs822020 |
CAS号: | 3606-45-9 |
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抑制剂描述: 产品名称:Dihydrosanguinarine 产品别名:见爱必信官网 英文别名:Dihydrosanguinarine 靶点:Alkaloids CAS:3606-45-9 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity.IC50 value:Target:in vitro: Dihydrosanguinarine showed much less cytotoxicity than sanguinarine: at the highest concentration tested (20 microM) and 24h exposure, dihydrosanguinarine decreased viability only to 52% . Dihydrosanguinarine showed the highest antifungal activity against B. cinerea Pers, with 95.16% mycelial growth inhibition at 50 μg/ml . dihydrosanguinarine showed the most potent leishmanicidal activities (IC(50) value: 0.014 microg/ml, respectively) .in vivo: Repeated dosing of DHSG for 90 days at up to 500 ppm in the diet (i.e. approximately 58 mg/kg/day) showed no evidence of toxicity in contrast to results published in the literature . 溶解性: 体外研究: 体内研究:
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